A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid

Castro, RESola, SMa, XMRamalho, RMKren, BTSteer, CJRodrigues, CMP2015-12-302015-12-302005JOURNAL OF HEPATOLOGY. - Vol. 42, n. 6 (JUN 2005), p. 897-9060168-8278http://hdl.handle.net/10451/21076Background/Aims: Ursodeoxycholic acid (UDCA) and its taurine-conjugated derivative, TUDCA, modulate cell death and cell cycle regulators, such as E2F-1 and p53. However, precise pathways underlying UDCA's effects are not fully understood. The aim of thisapplication/pdfengGastroenterology & HepatologyA distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acidjournal articlehttp://dx.doi.org/10.1016/j.jhep.2005.01.026