Félix, Isa BritoHenriques, Adriana2021-06-072021-06-072021Nurs Forum. 2021 Jun 10029-6473http://hdl.handle.net/10451/48380Copyright © 2021 Wiley Periodicals LLCAim: Identify the medication adherence determinants in older adults with multimorbidity and polypharmacy. Materials and methods: A cross-sectional study was conducted in a non-probabilistic sample of 245 adults ≥65 years recruited in a general medical ward of one teaching hospital. Data were collected during hospital stay using a face-to-face interview based on a set of validated questionnaires, such as the measure treatment adherence, the beliefs about medicines questionnaire-specific and the geriatric depression scale. Descriptive and multiple linear regression analysis were performed. Results: Participants' mean age was 78.32 (SD: 6.95) years and 50.6% were women. Older adults lived with an average of 7.51 (SD: 1.95) chronic conditions and had a mean of 7.95 (min. 4; max. 18) medications prescribed. The proportion of older adults adherent to medication was 43.7%. Depression ( β = -0.142; p = 0.031), beliefs about treatment necessity ( β = 0.306; p = 0.001) and concerns about the medication ( β = -0.204; p = 0.001) were found as independent determinants of adherence. Conclusion: Self-reported medication non-adherence appears to be common in older adults with multimorbidity and polypharmacy. Depression, necessity and concerns should be considered when assessing medication non-adherence in practice. This study will also contribute to develop an intervention to manage adherence in older people, as part of a doctoral research project.engBehavior determinantsMedication adherenceMultimorbidityOlder adultsPolypharmacyjournal article10.1111/nuf.126191744-6198