Bárbara, CristinaAlmeida, António Bugalho deStaats, Richard2022-04-212022-04-212020-11http://hdl.handle.net/10451/52490Sleep is a condition with reduction or absence of life supporting mechanism like alimentation, self-defence, or reproduction. It occupies about a third of the human life span and has been found in all animals including insects. Despite the intense research in recent years, several mysteries of sleep still need to be revealed. This manuscript aims to increase our knowledge of the effect of obstructive sleep apnea (OSA) on components of human homeostasis.engDistúrbios respiratórios do sonosistema imunológicometabolismo lipídicotemperaturasleep disordered breathingimmune systemlipid metabolismtemperaturedoctoral thesis101366345