Pessoa, João2021-10-112021-10-112021Trends Mol Med. 2021 Oct;27(10):928-9301471-4914http://hdl.handle.net/10451/49850© 2021 Elsevier Ltd. All rights reserved.Sutherland et al. recently reported the in vitro inhibition of Helicobacter hepaticus cytochrome c (cyt c) synthase, which may inactivate c-type cytochromes in this and in other pathogenic bacteria. Here, I discuss the impact of this work, which identifies this conserved synthase as a potential antibacterial target.engAntibacterial strategyC-type cytochromeCytochrome cCytochrome c synthaseHeme attachmentPeptideProspective antibacterial inhibition of c-type cytochrome synthesisjournal article10.1016/j.molmed.2021.07.0071471-499X