Pignata, ClaudioD'Assante, RobertaSousa, Ana E.2015-09-222015-09-222015Frontiers in Immunology | February 2015 | Volume 6 | Article 811664-3224http://dx.doi.org/ 10.3389/fimmu.2015.00081http://hdl.handle.net/10451/20114© 2015 Pignata, D’Assante and Sousa. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.engSevere combined immunodeficiencyDiGeorge syndromeFOXN1Central toleranceMedullary thymic epithelial cellsRag defectsjournal article