Rodrigues, CMPSola, SSilva, RBrites, D2015-12-302015-12-302000MOLECULAR MEDICINE. - Vol. 6, n. 11 (NOV 2000), p. 936-9461076-1551http://hdl.handle.net/10451/21043Background: The pathogenesis of bilirubin encephalopathy and Alzheimer's disease appears to result from accumulation of unconjugated bilirubin (UCB) and amyloid-beta (A beta) peptide, respectively, which may cause apoptosis. Permeabilization of the mitochapplication/pdfengBiochemistry & Molecular BiologyCell BiologyMedicine, Research & ExperimentalBilirubin and amyloid-beta peptide induce cytochrome c release through mitochondrial membrane permeabilizationjournal article