Stereo-EEG recording and minimally invasive treatment of a periventricular nodular heterotopy : two-in-one strategy

Franco, Ana CatarinaPeralta, Ana RitaMorgado, CarlosGonçalves Ferreira, AntónioRainha Campos, AlexandreBentes, Carla2021-02-012021-02-012020Clin Neurophysiol. 2020 May;131(5):1099-11011388-2457http://hdl.handle.net/10451/46094© 2020 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.Periventricular nodular heterotopias (PNHs) are malformations of cortical development. These are frequently associated with drug-resistant epilepsy. Stereo-electroencephalography (SEEG) is usually part of the epilepsy pre-surgical evaluation in order to find the epileptogenic zone (EZ). SEEG-guided radiofrequency-thermocoagulation (RF-TC) has been used to ablate or disrupt the EZ and proved to be effective, with seizure freedom rates of 38-50%, a responder rate of 81% and a favorable safety profile.engStereo-EEG recording and minimally invasive treatment of a periventricular nodular heterotopy : two-in-one strategyjournal article10.1016/j.clinph.2020.02.0161872-8952