Castro, RRivera, IStruys, EAJansen, EEWRavasco, PCamilo, MEBlom, HJJakobs, Cde Almeida, IT2015-12-302015-12-302003CLINICAL CHEMISTRY. - Vol. 49, n. 8 (AUG 2003), p. 1292-12960009-9147http://hdl.handle.net/10451/21242Background: The pathogenic mechanism of homocysteine's effect on cardiovascular risk is poorly understood. Recent studies show that DNA hypomethylation induced by increases in S-adenosylhomocysteine (AdoHcy), an intermediate of Hcy metabolism and a potentapplication/pdfengMedical Laboratory TechnologyIncreased, homocysteine and S-adenosylhomocysteine concentrations and DNA hypomethylation in vascular diseasejournal article