Duarte, NoeliaFerreira, Maria-Jose U.2015-12-302015-12-302007ORGANIC LETTERS. - Vol. 9, n. 3 (FEB 1 2007), p. 489-4921523-7060http://hdl.handle.net/10451/21438Two new diterpenes, lagaspholones A (1) and B (2), have been isolated from the methanolic extract of Euphorbia lagascae, along with the known compounds (+)-dehydrovomifoliol, scopoletin, dehydrodiconiferyl diacetate, 3-indolcarbaldehyde, and 4-hydroxy-3,5-dimethoxybenzaldehyde. Their structures were elucidated by spectroscopic methods. Compounds 1 and 2 contain the rare jatropholane-type skeleton, characterized by a 5:6:7:3 fused ring system. A possible biosynthetic pathway for lagaspholones is proposed.application/pdfengChemistry, Organicjournal articlehttp://dx.doi.org/10.1021/ol062854f