Differential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytes

Castro, Rui E.Amaral, Joana D.Sola, SusanaKren, Betsy T.Steer, Clifford J.Rodrigues, Cecilia M. P.2015-12-302015-12-302007AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. - Vol. 293, n. 1 (JUL 2007), p. G327-G3340193-1857http://hdl.handle.net/10451/21094Ursodeoxycholic ( UDCA) and tauroursodeoxycholic ( TUDCA) acids modulate apoptosis and regulate cell- cycle effectors, including cyclin D1. In contrast, deoxycholic acid ( DCA) induces cell death and cyclin D1. In this study, we explored the role of cycliapplication/pdfengGastroenterology & HepatologyPhysiologyDifferential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytesjournal articlehttp://dx.doi.org/10.1152/ajpgi.00093.2007