Utilize este identificador para referenciar este registo:
http://hdl.handle.net/10451/21265| Título: | Catechols from abietic acid Synthesis and evaluation as bioactive compounds |
| Autor: | Gigante, B Santos, C Silva, AM Curto, MJM Nascimento, MSJ Pinto, E Pedro, M Cerqueira, F Pinto, MM Duarte, MP Laires, A Rueff, J Goncalves, J Pegado, MI Valdeira, ML |
| Palavras-chave: | Biochemistry & Molecular Biology Chemistry, Medicinal Chemistry, Organic |
| Data: | 2003 |
| Editora: | PERGAMON-ELSEVIER SCIENCE LTD |
| Citação: | BIOORGANIC & MEDICINAL CHEMISTRY. - Vol. 11, n. 8 (APR 17 2003), p. 1631-1638 |
| Resumo: | Catechols from abietic acid were prepared by a short and good yielding chemical process and further evaluated for several biological activities namely, antifungal, antitumoral, antimutagenic, antiviral, antiproliferative and inhibition of nitric oxide. Their properties were compared with those of carnosic acid (6), a naturally occurring catechol with an abietane skeleton and known to possess potent antioxidant activity, as well as anticancer and antiviral properties. From all the synthetic catechols tested compound 2 showed the best activities, stronger than carnosic acid. (C) 2003 Elsevier Science Ltd. All rights reserved. |
| URI: | http://hdl.handle.net/10451/21265 |
| DOI: | http://dx.doi.org/10.1016/S0968-0896(03)00063-4 |
| ISSN: | 0968-0896 |
| Aparece nas colecções: | FF - Produção Científica 2000-2009 |
Ficheiros deste registo:
Não existem ficheiros associados a este registo.
Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.
