The ULisboa Repository - institutional repository of the University of Lisbon, is part of the RCAAP Project (Scientific Open Access Repositories of Portugal).
It is the collection of documents that form the intellectual, academic and scientific production of this university community. Its objectives are to gather, organize, disseminate and preserve the scientific production of ULisboa.
The ULisboa Repository comprises various types of documents, in digital format, resulting from the research activities carried out at the University, namely: doctoral theses, master's dissertations, articles from national and international scientific journals, communications to congresses and conferences, among others, of all scientific areas existing at the University.
Recent Submissions
Sustained macrophage reprogramming is required for CD8+ T cell–dependent long-term tumor eradication
Tumor-associated macrophages (TAM) exhibit a dual role in tumor progression and antitumor immunity. However, understanding the functional states and molecular mechanisms of antitumor TAMs remains a challenge. Herein, we show that intratumoral administration of a combination of agonists against TLR3&#x...
Intervenções psicológicas em casais com mulheres diagnosticadas com cancro da mama : uma revisão sistemática
O cancro da mama está associado a um impacto psicossocial considerável na vida das mulheres e dos seus parceiros, nos quais se reportam maiores níveis de distress psicológico, dificuldade sexual e menor satisfação marital. Atualmente, adota se uma perspetiva de impacto no casal enq...
Início de carreira na rede pública municipal da educação de Fortaleza : narrativas sobre como nos tornamos professoras
O início da carreira no magistério é um período marcado por muitas aprendizagens e desafios que surgem à medida em que ocorre a inserção no cotidiano escolar. Por essa razão, a presente pesquisa investiga o processo de construção da identidade profissional nos primeiros anos d...
1-Deoxysphingolipids
Sphingolipids (SLs) are fundamental components of eukaryotic cells. 1-Deoxysphingolipids differ structurally from canonical SLs as they lack the essential C1-OH group. Consequently, 1-deoxysphingolipids cannot be converted to complex sphingolipids and are not degraded over the canonical catabolic pathways. ...
5-(Hydroxyphenyl)-γ-Valerolactone-Sulfate, a Key Microbial Metabolite of Flavan-3-ols, Is Able to Reach the Brain: Evidence from Different in Silico, In Vitro and In Vivo Experimental Models
Phenolic compounds have been recognized as promising compounds for the prevention of chronic diseases, including neurodegenerative ones. However, phenolics like flavan-3-ols (F3O) are poorly absorbed along the gastrointestinal tract and structurally rearranged by gut microbiota, yielding smaller and more&#...
