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Candida auris uma ameaça crescente para a Saúde Pública
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Candida auris é um fungo emergente que apresenta uma séria ameaça à saúde global. A preocupação das entidades de saúde, incluindo o Centro de Controlo e Prevenção de Doenças (Centers for Disease Control and Prevention - CDC) e o Centro Europeu de Prevenção e Controlo de Doenças (European Centre for Disease Prevention and Control – ECDC), prende-se principalmente por algumas razões principais. É frequentemente resistente a múltiplos antifúngicos comumente usados para tratar infeções por Candida. É difícil a sua identificação pelos métodos laboratoriais padrão, podendo mesmo ser erroneamente identificada em laboratórios sem tecnologia específica. A identificação incorreta pode levar a uma gestão inadequada do indivíduo infetado. Foram registados surtos em várias partes do mundo, e pesquisas recentes sugerem que as temperaturas mais altas, provocadas pelo aquecimento global, podem levar a um aumento no número de casos. Por esse motivo, e de acordo com as entidades competentes, é necessária uma melhor identificação dos indivíduos infetados mais vulneráveis para reduzir o risco de contágio, sendo também importante identificar rapidamente C. auris num indivíduo hospitalizado, para que os serviços de saúde possam tomar precauções especiais para impedir a sua propagação. C. auris, com a sua capacidade de se disseminar rapidamente em indivíduos críticos, tem o potencial de se tornar um agente patogénico oportunista dominante nestas populações.
C. auris têm potencial para aumentar significativamente a morbilidade, a letalidade e comprometer as infra-estruturas e finanças dos serviços de saúde. O aumento do número de casos detetados num número cada vez maior de países e a identificação de isolados cada vez mais resistentes são situações particularmente preocupantes. As pesquisas atuais parecem ter impacto significado em resultados futuros para indivíduos infetados e instituições em todo o mundo.
O CDC e o ECDC incentivam à vigilância, à identificação e à notificação às autoridades de saúde públicas.
Candida auris is an emerging fungus that presents a serious threat to global health. The concern of health entities, including the Centers for Disease Control and Prevention (CDC) and the European Centre for Disease Prevention and Control (ECDC), is mainly related to some main reasons. It is often resistant to multiple antifungals commonly used to treat Candida infections. It is difficult to identify them by standard laboratory methods, and can even be erroneously identified in laboratories without specific technology. Incorrect identification can lead to inadequate management of the infected individual. Outbreaks have been recorded in various parts of the world, and recent research suggests that higher temperatures caused by global warming may lead to an increase in the number of cases. For this reason, and according to the competent authorities, better identification of the most vulnerable infected individuals is necessary to reduce the risk of contagion, and it is also important to quickly identify C. auris in a hospitalized individual, so that health services can take special precautions to prevent its spread. C. auris, with its ability to spread rapidly to critical individuals, has the potential to become a dominant opportunist pathogen in these populations. C. auris have the potential to significantly increase morbidity, lethality and compromise the infrastructure and finances of health services. The increase in the number of cases detected in an increasing number of countries and the identification of increasingly resistant isolates are particularly worrying situations. Current research seems to have a significant impact on future results for infected individuals and institutions around the world. The CDC and the ECDC encourage surveillance, identification and notification to public health authorities.
Candida auris is an emerging fungus that presents a serious threat to global health. The concern of health entities, including the Centers for Disease Control and Prevention (CDC) and the European Centre for Disease Prevention and Control (ECDC), is mainly related to some main reasons. It is often resistant to multiple antifungals commonly used to treat Candida infections. It is difficult to identify them by standard laboratory methods, and can even be erroneously identified in laboratories without specific technology. Incorrect identification can lead to inadequate management of the infected individual. Outbreaks have been recorded in various parts of the world, and recent research suggests that higher temperatures caused by global warming may lead to an increase in the number of cases. For this reason, and according to the competent authorities, better identification of the most vulnerable infected individuals is necessary to reduce the risk of contagion, and it is also important to quickly identify C. auris in a hospitalized individual, so that health services can take special precautions to prevent its spread. C. auris, with its ability to spread rapidly to critical individuals, has the potential to become a dominant opportunist pathogen in these populations. C. auris have the potential to significantly increase morbidity, lethality and compromise the infrastructure and finances of health services. The increase in the number of cases detected in an increasing number of countries and the identification of increasingly resistant isolates are particularly worrying situations. Current research seems to have a significant impact on future results for infected individuals and institutions around the world. The CDC and the ECDC encourage surveillance, identification and notification to public health authorities.
Descrição
Tese de mestrado, Análises Clínicas, 2021, Universidade de Lisboa, Faculdade de Farmácia.
Palavras-chave
Laboratório de análises clínicas Candida auris Emergente Resistência Teses de mestrado - 2021