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Antimicrobial effects of essential oils on oral microbiota biofilms: the toothbrush In vitro model
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Orientador(es)
Resumo(s)
The present investigation intended to evaluate the bacteriostatic and bactericidal abilities
of clove, oregano and thyme essential oils against oral bacteria in planktonic and biofilm states.
Furthermore, aiming to mimic everyday conditions, a toothbrush in vitro model was developed.
Determination of the minimum inhibitory concentration, minimum bactericidal concentration, minimum biofilm inhibitory concentration and minimum biofilm eradication concentration were achieved
using the microdilution procedure. To simulate the toothbrush environment, nylon fibers were inoculated with oral bacteria, which, after incubation to allow biofilm development, were submitted to
contact with the essential oils under study. Thyme and oregano essential oils revealed promising
antimicrobial effects, both in growth inhibition and the destruction of cells in planktonic and biofilm
states, while clove essential oil showed a weaker potential. Regarding the toothbrush in vitro model,
observation of the nylon fibers under a magnifying glass proved the essential oil anti-biofilm properties. Considering the effects observed using the in vitro toothbrush model, a realistic approximation
to oral biofilm establishment in an everyday use object, a putative application of essential oils as
toothbrush sanitizers to help prevent the establishment of bacterial biofilm can be verified.
Descrição
Research Areas: Infectious Diseases ; Pharmacology & Pharmacy
Palavras-chave
Oral microbiota Biofilm Essential oils Antimicrobial activity Toothbrush model
Contexto Educativo
Citação
Aires A, Barreto AS, Semedo-Lemsaddek T. 2021. Antimicrobial effects of essential oils on oral microbiota biofilms: the toothbrush In vitro model. Antibiotics. 10(1):21. Doi: 10.3390/antibiotics10010021
Editora
MDPI