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Effectiveness of high-intensity interval training combined with resistance training versus continuous moderate-intensity training combined with resistance training in patients with type 2 diabetes : a one-year randomized controlled trial

dc.contributor.authorMagalhães, João P.
dc.contributor.authorJúdice, Pedro B.
dc.contributor.authorRibeiro, Rogério
dc.contributor.authorAndrade, Rita
dc.contributor.authorRaposo, João
dc.contributor.authorDores, Hélder
dc.contributor.authorBicho, Manuel
dc.contributor.authorSardinha, Luís B.
dc.date.accessioned2018-11-27T17:06:05Z
dc.date.available2018-11-27T17:06:05Z
dc.date.issued2018
dc.description© 2018 John Wiley & Sons Ltdpt_PT
dc.description.abstractAims: To evaluate the impact of one-year high intensity interval training (HIIT) combined with resistance training (RT) vs continuous moderate intensity training (MCT) combined with RT on glycaemic control, body composition and cardiorespiratory fitness (CRF) in patients with type 2 diabetes. Materials and Methods: A randomized controlled trial included 96 participants with type 2 diabetes for a one-year supervised exercise intervention with three groups: Control, HIIT with RT and MCT with RT). The control group received standard counseling regarding general PA guidelines, with no structured exercise sessions. The main outcome variable was HbA1c (%). Secondary outcomes were other glycaemic variables, body composition, anthropometry measurements, CRF and enjoyment of exercise. Generalized estimating equations (GEE) were used to model outcomes. Results: Among the 96 participants enrolled in the intervention, 80 were randomized, with a mean (SD) age of 58.5 years (7.7) and a mean HbA1c of 7.2% (1.6). After adjusting the model for sex and total moderate-to-vigorous physical activity (MVPA), we found that both the MCT with RT (β, 0.003; P, 0.921) and the HIIT with RT (β, 0.025; P, 0.385) groups had no effect on HbA1c. A favourable effect was observed in the MCT with RT group, with a reduction in whole body fat index (β, −0.062; P, 0.022), android fat index (β, −0.010; P, 0.010) and gynoid fat index (β, −0.013; P, 0.014). Additionally, CRF increased during the intervention, but only in the MCT with RT group (β, 0.185; P, 0.019). Conclusions: The results from this study suggest that there was no effect of either MCT with RT or HIIT with RT on glycaemic control in individuals with type 2 diabetes. However, the combination of MCT and RT improved body composition and CRF following a one-year intervention.pt_PT
dc.description.sponsorshipJ. M., P. B. J. and R. R. are supported by fellowships from the Portuguese Foundation for Science and Technology (J. M. grant: SFRH/ BD/85742/2012; P. B. J. grant: SFRH/ BPD/115977/2016; R. R. grant: SFRH/BPD/110426/2015).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDiabetes Obes Metab. 2018;1–10pt_PT
dc.identifier.doi10.1111/dom.13551pt_PT
dc.identifier.issn1462-8902
dc.identifier.urihttp://hdl.handle.net/10451/35507
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherJohn Wiley and Sonspt_PT
dc.relationThe epidemic has gone global: Can physical activity patterns offset the harmful effects of sedentary behavior A trans-national prospective study from childhood to adulthood
dc.relationManaging diabetes in the real world: promoting gains in effectiveness from prevention to treatment
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/journal/14631326pt_PT
dc.subjectAbdominal fatpt_PT
dc.subjectBody compositionpt_PT
dc.subjectCardiorespiratory fitnesspt_PT
dc.subjectGlycemic controlpt_PT
dc.subjectHbA1cpt_PT
dc.subjectInterventionpt_PT
dc.subjectRCTpt_PT
dc.titleEffectiveness of high-intensity interval training combined with resistance training versus continuous moderate-intensity training combined with resistance training in patients with type 2 diabetes : a one-year randomized controlled trialpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberSFRH/BD/85742/2012
oaire.awardNumberSFRH/BPD/115977/2016
oaire.awardNumberSFRH/BPD/110426/2015
oaire.awardTitleThe epidemic has gone global: Can physical activity patterns offset the harmful effects of sedentary behavior A trans-national prospective study from childhood to adulthood
oaire.awardTitleManaging diabetes in the real world: promoting gains in effectiveness from prevention to treatment
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F85742%2F2012/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/OE/SFRH%2FBPD%2F115977%2F2016/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F110426%2F2015/PT
oaire.citation.titleDiabetes, Obesity and Metabolismpt_PT
oaire.fundingStreamSFRH
oaire.fundingStreamOE
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublicationf9f44136-6b9e-402d-b4b2-a56bde3b049f
relation.isProjectOfPublicationf65c7a56-d534-4ada-bbaa-138cc396ead3
relation.isProjectOfPublication35b01217-8f76-4158-9c26-0d22688558b1
relation.isProjectOfPublication.latestForDiscovery35b01217-8f76-4158-9c26-0d22688558b1

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