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Telemedicine as a tool for dietary intervention in NAFLD-HIV patients during the COVID-19 lockdown: a randomized controlled trial

dc.contributor.authorPolicarpo, Sara
dc.contributor.authorMachado, Mariana
dc.contributor.authorCortez-Pinto, Helena
dc.date.accessioned2023-02-22T12:09:40Z
dc.date.available2023-02-22T12:09:40Z
dc.date.issued2021
dc.description© 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.pt_PT
dc.description.abstractBackground & aims: Given reports of changes in dietary habits during covid-19 lockdown, our aim was to assess weight changes, over a 3-month Covid-19 national lockdown in a cohort of NAFLD-HIV patients on a dietary intervention trial. Methods: After NAFLD screening in an outpatient Infectious Diseases Clinic, NAFLD patients were randomly allocated to general dietary recommendations (SC group) or to a structured dietary intervention based on the Mediterranean diet (intervention group). During lockdown, follow-up consultations in the intervention group were done by video and/or phone. After 3 months of lockdown, all patients (intervention and SC group) consented to a telephone interview which aimed to characterize eating habits and lifestyle changes and evaluate stress and depression. Biochemical data when available, was compared between the peri-period of confinement. Results: One hundred and twelve patients were screened. From the 55 NAFDL identified, 27 were allocated to dietary intervention and 28 to SC and were followed before lockdown for a mean period of 5.0 ± 1.5 months in which SC group gained a median of 0.65 kg vs. a median loss of 1.5 kg in the intervention group (p < 0.001). During lockdown, 93.3% of patients in the SC group referred that "diet got worse" vs. 6.7% in the intervention group p < 0.01), and 35.3% vs. 15.7% (p = 0.014) reported increase in appetite, respectively. Both groups gained weight, SC group vs. 0.7 ± 1.7 kg in the intervention group, p < 0.001). Higher weight gain was associated with changes in the dietary pattern (3.8 ± 2.1 kg vs. 2.0 ± 1.3 kg in "no change in dietary pattern"; p = 0.002). Glucose blood levels increased after lockdown in the SC group, with a mean increase of 15 mg/dl (p = 0.023). The remaining metabolic parameters remained unchanged. Conclusion: The maintenance of dietary intervention, using telemedicine, can mitigate the adverse change in dietary habits and physical activity pattern, preventing a substantial increase in body weight.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationClin Nutr ESPEN. 2021 Jun;43:329-33pt_PT
dc.identifier.doi10.1016/j.clnesp.2021.03.031pt_PT
dc.identifier.eissn2405-4577
dc.identifier.urihttp://hdl.handle.net/10451/56403
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/clinical-nutrition-espenpt_PT
dc.relation.publisherversionhttps://clinicalnutritionespen.com/pt_PT
dc.subjectCOVID-19 lockdownpt_PT
dc.subjectDietary interventionpt_PT
dc.subjectNAFLDpt_PT
dc.subjectNutritionpt_PT
dc.titleTelemedicine as a tool for dietary intervention in NAFLD-HIV patients during the COVID-19 lockdown: a randomized controlled trialpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage334pt_PT
oaire.citation.startPage329pt_PT
oaire.citation.titleClinical Nutrition ESPENpt_PT
oaire.citation.volume43pt_PT
person.familyNamePolicarpo
person.familyNameMachado
person.familyNameCortez-Pinto
person.givenNameSara
person.givenNameMariana
person.givenNameHelena
person.identifier.ciencia-idA01C-0511-C986
person.identifier.orcid0000-0001-8594-1720
person.identifier.orcid0000-0001-7769-7860
person.identifier.orcid0000-0002-8537-8744
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication18ef9bc3-1f7a-414b-b2aa-a1163f2f2367
relation.isAuthorOfPublicationcfad9e93-f680-4e18-864f-b3954ee025ed
relation.isAuthorOfPublication91fdb4b3-d491-4e67-94ff-dcf5013fa1a7
relation.isAuthorOfPublication.latestForDiscoverycfad9e93-f680-4e18-864f-b3954ee025ed

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