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Past present and prospective : drivers of innovation in pharma
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Exploramos os principais motores da inovação na indústria farmacêutica através da análise dos
investimentos em I&D (Investigação e Desenvolvimento) dos membros da Organização
Pharmaceutical Research and Manufacturers of America (PhRMA) entre 1983 e 2021.
Utilizando uma análise PEST (Política, Económica, Social e Tecnológica), examinamos como
os fatores externos influenciaram a evolução dos investimentos em I&D ao longo de quase
quatro décadas. A análise revela que fatores políticos, como as políticas governamentais e
normas regulatórias, foram cruciais durante períodos como o Boom da Biotecnologia e a
pandemia COVID-19. As condições económicas, incluindo o impacto da Crise Financeira
Global, mostraram afetar diretamente os gastos em I&D, com a recuperação levando ao
restabelecimento do crescimento. Fatores sociais, como o aumento da procura por medicina
personalizada e a sensibilização para a saúde pública, impulsionaram mudanças nas prioridades
de I&D, particularmente durante o Projeto Genoma Humano e o desenvolvimento da
tecnologia de mRNA. Os avanços tecnológicos têm sido consistentemente os motores mais
significativos do crescimento em I&D, com avanços na biotecnologia e na tecnologia de
mRNA a conduzir a aumentos substanciais no investimento. Os resultados destacam o impacto
de fatores externos no investimento I&D da indústria farmacêutica, oferecendo prespectivas
sobre tendências futuras e potenciais considerações estratégicas. Este estudo destaca a
importância da utilização dos fatores PEST para sustentar a inovação e manter uma vantagem
competitiva na indústria.
We explore the key drivers of innovation in the pharmaceutical industry by analyzing R&D (Research and Development) expenditures from Pharmaceutical Research and Manufacturers of America (PhRMA) member companies between 1983 to 2021. Using a PEST (Political, Economic, Social, and Technological) Analysis, the study examines how external factors have influenced the evolution of R&D investments over nearly four decades. The analysis reveals that political factors, such as government policies and regulatory frameworks, have been crucial during periods like the Biotechnology Boom and the COVID-19 pandemic. Economic conditions, including the impact of the Global Financial Crisis, have shown to directly affect R&D expenditures, with recovery, leading to restore growth. Social factors, such as the increasing demand for personalized medicine and public health awareness, have driven shifts in R&D priorities, particularly during the Human Genome Project and the development of mRNA technology. Technological advancements have consistently been the most significant drivers of R&D growth, with breakthroughs in biotechnology and mRNA technology leading to substantial increases in investment. The results highlight the critical role of external factors in shaping the pharmaceutical industry's R&D field, offering insights into future trends and strategic considerations. This study highlights the importance in navigating with the usage of PEST factors to sustain innovation and maintain a competitive edge in the industry.
We explore the key drivers of innovation in the pharmaceutical industry by analyzing R&D (Research and Development) expenditures from Pharmaceutical Research and Manufacturers of America (PhRMA) member companies between 1983 to 2021. Using a PEST (Political, Economic, Social, and Technological) Analysis, the study examines how external factors have influenced the evolution of R&D investments over nearly four decades. The analysis reveals that political factors, such as government policies and regulatory frameworks, have been crucial during periods like the Biotechnology Boom and the COVID-19 pandemic. Economic conditions, including the impact of the Global Financial Crisis, have shown to directly affect R&D expenditures, with recovery, leading to restore growth. Social factors, such as the increasing demand for personalized medicine and public health awareness, have driven shifts in R&D priorities, particularly during the Human Genome Project and the development of mRNA technology. Technological advancements have consistently been the most significant drivers of R&D growth, with breakthroughs in biotechnology and mRNA technology leading to substantial increases in investment. The results highlight the critical role of external factors in shaping the pharmaceutical industry's R&D field, offering insights into future trends and strategic considerations. This study highlights the importance in navigating with the usage of PEST factors to sustain innovation and maintain a competitive edge in the industry.
Descrição
Tese de mestrado, Engenharia Farmacêutica, 2024, Universidade de Lisboa, Faculdade de Farmácia.
Palavras-chave
Pharmaceutical innovation R&D Expenditures PEST Analysis Innovation drivers Technological advancements Teses de mestrado - 2024