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A longitudinal study of neurological soft signs from late childhood into early adulthood

dc.contributor.authorMartins, Isabel
dc.contributor.authorLauterbach, Martin
dc.contributor.authorSlade, Peter
dc.contributor.authorLuís, Henrique
dc.contributor.authorDeRouen, Timothy
dc.contributor.authorMartin, Michael
dc.contributor.authorCaldas, Alexandre
dc.contributor.authorLeitão, Jorge
dc.contributor.authorRosenbaum, Gail
dc.contributor.authorTownes, Brenda
dc.date.accessioned2018-07-20T14:58:08Z
dc.date.available2018-07-20T14:58:08Z
dc.date.issued2008
dc.description.abstractNeurological examination of children includes the screening for soft neurological signs (NSS). There is little knowledge about their evolution during adolescence, except that their lasting presence has been associated with developmental, psychological, and cognitive disorders.We report the results of a NSS exam (assessing gross and fine motor function and the presence of hyperactivity and motor impersistence) over a 5-year period, among a group of healthy children who were followed annually as part of a dental study. Their ages ranged from 11 to 15 years at onset to 14 to 18 years at the end. Participants were divided into four groups by age (younger and older) and sex.At the first evaluation there were 191 males and 150 females. NSS score diminished both with increasing age and follow-up time in both groups, but at different rates in males and females. Females reached the lowest scores two years before the younger subgroup of males.These results show that NSS change rapidly in adolescence and at different rates in males and females, which must be taken into account in clinical contexts. The evolution of NSS suggests that they are a signature of neural development.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMartins I, Lauterbach M, Slade P, et al. A longitudinal study of neurological soft signs from late childhood into early adulthood. Developmental Medicine & Child Neurology. 2008;50:602-607.pt_PT
dc.identifier.doi10.1111/j.1469-8749.2008.03043.xpt_PT
dc.identifier.urihttp://hdl.handle.net/10451/34274
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.titleA longitudinal study of neurological soft signs from late childhood into early adulthoodpt_PT
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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