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Management of life-threatening ventricular arrhythmias: what is going on with autonomic neuromodulation

dc.contributor.authorJacinto, Sofia
dc.contributor.authorReis, João
dc.contributor.authorOliveira, Mario
dc.date.accessioned2024-06-06T13:33:05Z
dc.date.available2024-06-06T13:33:05Z
dc.date.issued2024
dc.description© 2024 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)pt_PT
dc.description.abstractElectrical storm (ES), characterized by recurrent and frequent episodes of potentially life-threatening ventricular arrhythmias (VA), is a relatively common condition, primarily seen in patients with structural heart disease and implantable cardioverter-defibrillators (ICD). It is a complex severe clinical situation, associated with high mortality and low quality of life. Electrical storm management has evolved over the years, with anti-arrhythmic drugs, introduced in the 1950s, followed by the ICD in the 1980s. In the 21st century, radiofrequency catheter ablation, three-dimensional electroanatomic mapping and advanced cardiac imaging have provided a better understanding of the arrhythmic mechanisms, allowing substrate modification, and refining ES management. However, ES is still associated with significant residual morbidity and mortality. In recent years, more attention has been given to autonomic nervous system dysregulation as a perpetrator of arrhythmias, and to the role of innovative techniques of neuromodulation in the prevention and treatment of refractory recurrent VA.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRev Port Cardiol. 2024 Jun;43(6):357-359pt_PT
dc.identifier.doi10.1016/j.repc.2023.11.004pt_PT
dc.identifier.eissn2174-2030
dc.identifier.issn0870-2551
dc.identifier.urihttp://hdl.handle.net/10451/64998
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/revista-portuguesa-de-cardiologiapt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.titleManagement of life-threatening ventricular arrhythmias: what is going on with autonomic neuromodulationpt_PT
dc.title.alternativeManejo de arritmias ventriculares potencialmente fatais: o papel da modulação autonómicapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage359pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage357pt_PT
oaire.citation.titleRevista Portuguesa de Cardiologiapt_PT
oaire.citation.volume43pt_PT
person.familyNameJacinto
person.familyNameMartins Oliveira
person.givenNameSofia
person.givenNameMario Joao
person.identifier.ciencia-id2312-2190-19B2
person.identifier.orcid0000-0002-3138-1892
person.identifier.orcid0000-0002-8371-8354
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication0edc534c-aa39-42b9-9ffc-bcd205ac1a06
relation.isAuthorOfPublication81e0b444-8832-47a8-a911-2f89eb33545d
relation.isAuthorOfPublication.latestForDiscovery81e0b444-8832-47a8-a911-2f89eb33545d

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