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Chemical composition and antibacterial activity of essential oils from the medicinal plant Mentha cervina L. grown in Portugal
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Orientador(es)
Resumo(s)
Mentha cervina is a medicinal plant traditionally
used in Portugal in folk medicine, in different gastric
disorders and inflammations of the respiratory tract. In
order to validate those traditional uses, M. cervina essential
oils (EOs) were characterized by GC and GC–MS and their
antimicrobial activity was tested against 23 bacterial strains
(including multiresistant strains). The EOs were dominated
by the monoterpenes pulegone (52–75%), isomenthone
(8–24%), limonene (4–6%), and menthone (1–2%). The
antibacterial activity of these EOs was compared to that of
the main components standards. The most effective antibacterial
activity was expressed by the EOs against the
Gram-negative bacteria, Escherichia coli and Acinetobacter
baumanni, with MIC values of 1 mg/ml. The EOs complex mixtures were more active than the individual
aromatic components supporting the hypothesis that the
EOs antibacterial activity is a function of the synergistic
effect of their different aromatic components. These results
show the potential role of M. cervina EOs as antibacterial
agents and validate the traditional use of this plant.
Descrição
Palavras-chave
Mentha cervina Lamiaceae GC GC-MS essential oils monoterpenes antimicrobial activity MIC
Contexto Educativo
Citação
"Medicinal Chemistry Research". ISSN 1554-8120. 21 (2012) 3485-3490