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A bioquímica clínica no acompanhamento da grávida: função hepática e patologias associadas
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Resumo(s)
O presente documento divide-se em duas partes: o relatório de estágio (Parte I) e a monografia (Parte II).
O relatório refere-se ao estágio curricular do 2º semestre do 2º ano do Mestrado de Análises Clínicas, da Faculdade de Farmácia da Universidade de Lisboa, tendo decorrido no Laboratório de Análises Clínicas Fernanda Galo, em Tomar. São descritos os equipamentos e respetivas metodologias, a forma como é realizado o controlo de qualidade e algumas das interferências possíveis nas áreas pré-analítica, bioquímica, hematologia e imunologia.
A monografia está inserida na área da Bioquímica, dando relevância à mulher grávida e às alterações fisiológicas que esta apresenta, com foco na função hepática. São abordados temas como etiologia, diagnóstico através de manifestações clínicas e achados laboratoriais, bem como complicações e tratamento de duas patologias exclusivas da gravidez: colestase intra-hepática e síndrome HELLP (hemólise, enzimas hepáticas elevadas, plaquetas baixas).
This document is divided into two parts: the internship report (Part I) and the monograph (Part II). The report refers to the curricular internship of the 2nd semester of the 2nd year of the Master's Degree in Clinical Analysis at the Faculty of Pharmacy of the University of Lisbon, which took place at the Fernanda Galo Clinical Analysis Laboratory in Tomar. The equipment and respective methodologies are described, as well as how quality control is carried out and some of the possible interferences in the pre-analytical, biochemistry, hematology and immunology areas. The monograph is inserted in the area of Biochemistry, giving relevance to pregnant women and the physiological changes they present, with a focus on liver function. Topics such as etiology, diagnosis through clinical manifestations and laboratory findings, as well as complications and treatment of two pathologies exclusive to pregnancy are covered: intrahepatic cholestasis and HELLP syndrome (hemolysis, elevated liver enzymes, low platelets).
This document is divided into two parts: the internship report (Part I) and the monograph (Part II). The report refers to the curricular internship of the 2nd semester of the 2nd year of the Master's Degree in Clinical Analysis at the Faculty of Pharmacy of the University of Lisbon, which took place at the Fernanda Galo Clinical Analysis Laboratory in Tomar. The equipment and respective methodologies are described, as well as how quality control is carried out and some of the possible interferences in the pre-analytical, biochemistry, hematology and immunology areas. The monograph is inserted in the area of Biochemistry, giving relevance to pregnant women and the physiological changes they present, with a focus on liver function. Topics such as etiology, diagnosis through clinical manifestations and laboratory findings, as well as complications and treatment of two pathologies exclusive to pregnancy are covered: intrahepatic cholestasis and HELLP syndrome (hemolysis, elevated liver enzymes, low platelets).
Descrição
Tese de mestrado, Análises Clínicas, 2024, Universidade de Lisboa, Faculdade de Farmácia.
Palavras-chave
Bioquímica Hematologia Imunologia Gravidez Função hepática Teses de mestrado - 2024