| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 1.62 MB | Adobe PDF |
Advisor(s)
Abstract(s)
Sleep-wake cycle is probably the most truthful signature of life. These unavoidable interchangeable states are together the matrix for all that occurs in physiology, and its rhythms are regulated by homeostatic and circadian processes involving different neuronal structures and distinct neural substrates. Hypothalamic regulation of sleep-wake cycle becomes of relevance as several neuropeptide-producing neurons involved in sleep and wakefulness regulation are located there. In this chapter, we provide a review of the hypothalamic regulation of sleep-wake cycle, focusing on the hypocretin system and melanin-concentrating hormone (MCH)-producing neurons located in the lateral hypothalamic area (LHA).
Description
© 2018 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords
Hypothalamus Sleep-wake Circadian rhythm Hypocretin Orexin
Pedagogical Context
Citation
Miguel Meira e Cruz, Sérgio Matoso Laranjo and Isabel Rocha (November 5th 2018). Hypothalamic Control of Sleep-Wake Circadian Cycle, Hypothalamus in Health and Diseases, Stavros J. Baloyannis and Jan Oxholm Gordeladze, IntechOpen,
Publisher
IntechOpen