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Cancer wasting and quality of life react to early individualized nutritional counselling!

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dc.contributor.authorRavasco, Paula
dc.contributor.authorMonteiro Grillo, Isabel
dc.contributor.authorCamilo, Maria
dc.date.accessioned2021-05-13T15:21:05Z
dc.date.available2021-05-13T15:21:05Z
dc.date.issued2007
dc.description© 2006 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.pt_PT
dc.description.abstractTo devise a meaningful nutritional therapy in cancer, a greater understanding of nutritional dimensions as well as patients' expectations and disease impact is essential. We have shown that nutritional deterioration in patients with gastrointestinal and head and neck cancer was multifactorial and mainly determined by the tumour burden and location. In a larger cohort, stage and location were yet again the major determinants of patients' quality of life (QoL), despite the fact that nutritional deterioration combined with intake deficits were functionally more relevant than cancer stage. Based on this framework, the potential role of integrated oral nutritional support on outcomes was investigated. In a pilot study using individualized nutritional counselling on a heterogeneous patient population, the achieved improvement of nutritional intake was proportional to a better QoL. The role of early nutritional support was further analysed in a prospective randomized controlled trial in head and neck cancer patients stratified by stage undergoing radiotherapy. Pre-defined outcomes were: nutritional status and intake, morbidity and QoL, at the end and 3 months after radiotherapy. Nutritional interventions, only given during radiotherapy, consisted of three randomization arms: (1) individualized nutritional counselling vs. (2) ad libitum diet+high protein supplements vs. (3) ad libitum diet. Nutritional interventions 1 and 2 positively influenced outcomes during radiotherapy; however, 3 months after its completion individualized nutritional counselling was the single method capable of sustaining a significant impact on patients' outcomes. The early provision of the appropriate mixture of foods and textures using regular foods may modulate outcomes in cancer patients.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationClin Nutr. 2007 Feb;26(1):7-15pt_PT
dc.identifier.doi10.1016/j.clnu.2006.10.005pt_PT
dc.identifier.eissn1532-1983
dc.identifier.issn0261-5614
dc.identifier.urihttp://hdl.handle.net/10451/47841
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/clinical-nutritionpt_PT
dc.relation.publisherversionhttps://www.clinicalnutritionjournal.com/pt_PT
dc.subjectCancerpt_PT
dc.subjectNutritional counsellingpt_PT
dc.subjectDietpt_PT
dc.subjectNutritional statuspt_PT
dc.subjectMorbiditypt_PT
dc.subjectQuality of lifept_PT
dc.titleCancer wasting and quality of life react to early individualized nutritional counselling!pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage15pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage7pt_PT
oaire.citation.titleClinical Nutritionpt_PT
oaire.citation.volume26pt_PT
person.familyNameRavasco
person.familyNamemonteiro grillo
person.givenNamePaula
person.givenNameisabel
person.identifier381093
person.identifier.ciencia-id2E1E-155A-9B23
person.identifier.orcid0000-0002-6056-8269
person.identifier.orcid0000-0002-2481-5576
person.identifier.scopus-author-id6602551513
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationc44c651e-a6a4-4755-a6b6-2431eef3ea93
relation.isAuthorOfPublication2c5b91e4-fc73-4396-b483-95dc9e893633
relation.isAuthorOfPublication.latestForDiscoveryc44c651e-a6a4-4755-a6b6-2431eef3ea93

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