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A systematic approach for designing a HBM Pilot Study for Europe

dc.contributor.authorBecker, Kerstin
dc.contributor.authorSeiwert, Margarete
dc.contributor.authorCasteleyn, Ludwine
dc.contributor.authorJoas, Reinhard
dc.contributor.authorJoas, Anke
dc.contributor.authorBiot, Pierre
dc.contributor.authorAerts, Dominique
dc.contributor.authorCastano, Argelia
dc.contributor.authorEsteban, Marta
dc.contributor.authorAngerer, Jürgen
dc.contributor.authorKoch, Holger M.
dc.contributor.authorSchoeters, Greet
dc.contributor.authorDen Hond, Elly
dc.contributor.authorSepai, Ovnair
dc.contributor.authorExley, Karen
dc.contributor.authorKnudsen, Lisbeth E.
dc.contributor.authorHorvat, Milena
dc.contributor.authorBloemen, Louis
dc.contributor.authorKolossa-Gehring, Marike
dc.contributor.authorDEMOCOPHES consortium
dc.date.accessioned2015-03-23T10:37:33Z
dc.date.available2015-03-23T10:37:33Z
dc.date.issued2014
dc.description© 2013 Elsevier GmbH. All rights reserved.por
dc.description.abstractThe objective of COPHES (Consortium to Perform Human biomonitoring on a European Scale) was to develop a harmonised approach to conduct human biomonitoring on a Europeanscale. COPHES developed a systematic approach for designing and conducting a pilot study for an EU-wide cross-sectional human biomonitoring (HBM) study and for the implementation of the fieldwork procedures. The approach gave the basis for discussion of the main aspects of study design and conduct, and provided a decision making tool which can be applied to many other studies. Each decision that had to be taken was listed in a table of options with their advantages and disadvantages. Based on this the rationale of the decisions could be explained and be transparent. This was important because an EU-wide HBM study demands openness of all decisions taken to encourage as many countries as possible to participate and accept the initiative undertaken. Based on this approach the following study design was suggested: a cross-sectional study including 120 children aged 6–11 years and their mothers aged up to 45 years from each participating country. For the pilot study the children should be sampled in equal shares in an urban and a rural location. Only healthy children and mothers (no metabolic disturbances) should be included, who have a sufficient knowledge of the local language and have been living at least for 5 years at the sampling location. Occupational exposure should not be an exclusion criterion. Recruitment should be performed via inhabitant registries or schools as an alternative option. Measures suitable to increase the response rate should be applied. Preferably, the families should be visited at home and interviewed face-to-face. Various quality control measures to guarantee a good fieldwork performance were recommended.eng
dc.description.sponsorshipEuropean Commission, DG for Researchand Innovation (RTD), who funded COPHES in the 7th Framework Programme (DG Research – No. 244237) and DG Environment,who co-funded DEMOCOPHES under the LIFE+ Programme (DG Environment-Life09 ENV/BE000410) together with the participating countries.eng
dc.identifier.citationInternational Journal of Hygiene and Environmental Health 217 (2014) 312–322eng
dc.identifier.issn1438-4639
dc.identifier.urihttp://dx.doi.org/10.1016/j.ijheh.2013.07.004
dc.identifier.urihttp://hdl.handle.net/10451/17770
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relationCOPHES / DEMOCOPHESpor
dc.relation.publisherversionThe definitive version is available at http://www.sciencedirect.comeng
dc.subjectCOPHESeng
dc.subjectStudy designeng
dc.subjectHBMeng
dc.subjectFieldworkeng
dc.subjectHarmonisationeng
dc.subjectDEMOCOPHESeng
dc.titleA systematic approach for designing a HBM Pilot Study for Europeeng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleInternational Journal of Hygiene and Environmental Healtheng
rcaap.rightsclosedAccesspor
rcaap.typearticlepor

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