Preclinical randomized controlled trial of bilateral discectomy versus bilateral discopexy in Black Merino sheep temporomandibular joint: TEMPOJIMS – Phase 1- histologic, imaging and body weight results

The role of temporomandibular joint (TMJ) surgery is not well defined due to a lack of quality randomized controlled clinical trials, comparing different TMJ surgical treatments with medical and placebo interventions. The temporomandibular joint interposal study (TEMPOJIMS) is a rigorous preclinical trial divided in 2 phases. In phase 1 the authors investigated the role of the TMJ disc and in phase 2 the authors evaluated 3 different interposal materials. The present work of TEMPOJIMS - phase 1, aims to evaluate histopathologic and imaging changes of bilateral discectomy and discopexy in Black Merino sheep TMJ, using a high-quality trial following the ARRIVE guidelines.

Descrição

Palavras-chave

Animals Body weight Female Mandibular condyle Sheep Temporomandibular joint Temporomandibular joint disc Tomography, X-Ray computed

URI

http://hdl.handle.net/10451/47343

Citação

Journal of Cranio-Maxillofacial Surgery, Volume 46, Issue 4, 2018, Pages 688-696

Editora

Elsevier

DOI

10.1016/j.jcms.2018.01.006

Coleções

FM - Artigos em Revistas Internacionais

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