Logo do repositório
 
Publicação

Biological treatments for temporomandibular joint disc disorders : strategies in tissue engineering

2021Artigo científico Acesso aberto
Ver registo simples
dc.contributor.authorTrindade, Daniela
dc.contributor.authorCordeiro, Rachel
dc.contributor.authorJosé, Henrique Cardoso
dc.contributor.authorÂngelo, David
dc.contributor.authorAlves, Nuno
dc.date.accessioned2021-06-23T12:59:10Z
dc.date.available2021-06-23T12:59:10Z
dc.date.issued2021
dc.description© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).pt_PT
dc.description.abstractThe temporomandibular joint (TMJ) is an important structure for the masticatory system and the pathologies associated with it affect a large part of the population and impair people’s lifestyle. It comprises an articular disc, that presents low regeneration capacities and the existing clinical options for repairing it are not effective. This way, it is imperative to achieve a permanent solution to guarantee a good quality of life for people who suffer from these pathologies. Complete knowledge of the unique characteristics of the disc will make it easier to achieve a successful tissue engineering (TE) construct. Thus, the search for an effective, safe and lasting solution has already started, including materials that replace the disc, is currently growing. The search for a solution based on TE approaches, which involve regenerating the disc. The present work revises the TMJ disc characteristics and its associated diseases. The different materials used for a total disc replacement are presented, highlighting the TE area. A special focus on future trends in the field and part of the solution for the TMJ problems described in this review will involve the development of a promising engineered disc approach through the use of decellularized extracellular matrices.pt_PT
dc.description.sponsorshipThis work is supported by the Fundação para a Ciência e a Tecnologia (FCT) and Centro2020 through the Project references: UIDB/04044/2020; UIDP/04044/2020; PAMI—ROTEIRO/0328/2013 (Nº 022158), MATIS (CENTRO-01-0145-FEDER-000014), and BIODISCUS (CENTRO-01-0247-FEDER-039969).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBiomolecules 2021,11, 93pt_PT
dc.identifier.doi10.3390/biom11070933pt_PT
dc.identifier.eissn2218-273X
dc.identifier.urihttp://hdl.handle.net/10451/48718
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationCENTRO-01-0145-FEDER-000014pt_PT
dc.relationCentre for Rapid and Sustainable Product Development
dc.relationCentre for Rapid and Sustainable Product Development
dc.relation.publisherversionhttps://www.mdpi.com/journal/biomoleculespt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2218-273X/11/7/933pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectTemporomandibular joint discpt_PT
dc.subjectFibrocartilagept_PT
dc.subjectDisc dysfunctionspt_PT
dc.subjectTissue engineeringpt_PT
dc.subjectDecellularizationpt_PT
dc.titleBiological treatments for temporomandibular joint disc disorders : strategies in tissue engineeringpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleCentre for Rapid and Sustainable Product Development
oaire.awardTitleCentre for Rapid and Sustainable Product Development
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04044%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04044%2F2020/PT
oaire.citation.titleBiomoleculespt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameÂngelo
person.givenNameDavid
person.identifier.ciencia-id2C1B-F1D5-5A08
person.identifier.orcid0000-0001-8411-9946
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication17926c30-4672-46f2-a819-657463e3c725
relation.isAuthorOfPublication.latestForDiscovery17926c30-4672-46f2-a819-657463e3c725
relation.isProjectOfPublication50028230-5ebf-40df-8bc0-4ed98af652f8
relation.isProjectOfPublicationad0b2a3a-96af-4b52-b0a3-b423fd046066
relation.isProjectOfPublication.latestForDiscovery50028230-5ebf-40df-8bc0-4ed98af652f8

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura
Nome:
Biological_treatments.pdf
Tamanho:
1.31 MB
Formato:
Adobe Portable Document Format
Ver/Abrir

Coleções

FM - Artigos em Revistas Internacionais