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Depth Concentration Profiles Obtained by Carbon Furnace Atomic Absorption Spectrometry for Nickel and Aluminium in Human Skin

dc.contributor.authorAlder, John F.
dc.contributor.authorBatoreu, Maria C. C.
dc.contributor.authorPearse, Anthony D.
dc.contributor.authorMarks, Ronald
dc.date.accessioned2017-07-27T12:11:47Z
dc.date.available2017-07-27T12:11:47Z
dc.date.issued1986-10
dc.description.abstractCarbon furnace atomic absorption spectrometry was used to detect nickei and aluminium within the skin after topical application of materiais containing these substances. Determination of the metals at particular depths within the skin was achieved by horizontal sectioning of the biopsies and analysis of the 20-30 tg skin samples obtained directly by dry ashing and atomising the solid skin sample in the furnace. The method was validated using wet ashed guinea pig skin samples and standard additions procedures and standard deviation data established using gelatine samples. Care was taken in developing the sample preparation procedure to assure no contamination of the skin sample by trace metals. The data obtained indicate that there is an apparent accumulation of nickel in fixed positions in the skin, perhaps associated with a higher density of Langerhans cells in these positions.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJournal of Analytical Atomic Spectrometry.1986;1(5):365-367pt_PT
dc.identifier.doihttp://dx.doi.org/10.1039/JA9860100365pt_PT
dc.identifier.issn0267-9477
dc.identifier.urihttp://hdl.handle.net/10451/28488
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relation.publisherversionhttp://pubs.rsc.org/en/content/articlepdf/1986/ja/ja9860100365pt_PT
dc.subjectskinpt_PT
dc.subjectnickel determinationpt_PT
dc.subjectaluminium determinationpt_PT
dc.subjectatomic absorption spectrometrypt_PT
dc.subjectLangerhans cellspt_PT
dc.titleDepth Concentration Profiles Obtained by Carbon Furnace Atomic Absorption Spectrometry for Nickel and Aluminium in Human Skinpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage367pt_PT
oaire.citation.startPage365pt_PT
oaire.citation.titleJournal of Analytical Atomic Spectrometrypt_PT
oaire.citation.volume1pt_PT
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT

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