Logo do repositório
 
Publicação

Milk enriched with phytosterols reduces plasma cholesterol levels in healthy and hypercholesterolemic subjects

2007Artigo científico Acesso restrito
Ver registo simples
dc.contributor.authorGonçalves, Sónia
dc.contributor.authorMaria, Vasco
dc.contributor.authorSilva-Herdade, Ana S.
dc.contributor.authorMartins e Silva, João
dc.contributor.authorSaldanha, Carlota
dc.date.accessioned2020-10-22T13:04:04Z
dc.date.available2020-10-22T13:04:04Z
dc.date.issued2007
dc.descriptionCopyright © 2007 Published by Elsevier Inc.pt_PT
dc.description.abstractThe consumption of plant sterols has been shown to decrease plasma concentrations of cholesterol without adverse effects in human subjects. To evaluate if milk would be a good vehicle for phytosterols to lower plasma levels of cholesterol, we performed a randomized blind study with healthy subjects (n = 22) and hypercholesterolemic patients (n = 19), both groups treated with phytosterol-enriched milk (2 g/d). Another hypercholesterolemic group (n = 15) was used as a control group. Lipid profile and biochemical, hematologic, and hemorheological parameters were determined at the beginning and after 15 and 30 days of milk beverage intake. After 15 days of treatment, healthy individuals showed lowered total cholesterol and LDL-C levels, by 8.31% (P = .05) and 11% (P < .05), respectively. After 30 days of the trial, these values did not change significantly. Hypercholesterolemic patients treated with phytosterol-enriched milk demonstrated significantly diminished levels of total cholesterol and LDL-C concentrations, by 9.62% (P < .05) and 12.20 % (P < .05), respectively. After 30 days, an increase in the total cholesterol and LDL-C levels was observed for hypercholesterolemic subjects, 6.69% (P < .05) and 8.68% (P < .05), respectively. In the hypercholesterolemic control subjects, no difference was found between plasma levels of total cholesterol, high-density lipoprotein cholesterol, and LDL-C. Only healthy subjects showed significant changes during the intake of phytosterol-enriched milk. The results obtained indicate that phytosterol-enriched milk is a good vehicle for reducing plasma cholesterol in hypercholesterolemic subjects.pt_PT
dc.description.sponsorshipThis study was supported by a grant from Lactogal SA, Porto, Portugal.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationNutrition Research 27 (2007) 200–205pt_PT
dc.identifier.doi10.1016/j.nutres.2007.03.003pt_PT
dc.identifier.issn0271-5317
dc.identifier.urihttp://hdl.handle.net/10451/44638
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/nutrition-researchpt_PT
dc.subjectHypercholesterolemic subjectspt_PT
dc.subjectPhytosterolspt_PT
dc.subjectLipidpt_PT
dc.subjectFunctional foodpt_PT
dc.subjectPlasma viscositypt_PT
dc.subjectErythrocyte aggregationpt_PT
dc.titleMilk enriched with phytosterols reduces plasma cholesterol levels in healthy and hypercholesterolemic subjectspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage205pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage200pt_PT
oaire.citation.titleNutrition Researchpt_PT
oaire.citation.volume27pt_PT
person.familyNameGonçalves
person.familyNameMaria
person.familyNameSilva-Herdade
person.familyNameSaldanha
person.givenNameSónia
person.givenNameVasco
person.givenNameAna S.
person.givenNameCarlota
person.identifier749915
person.identifier53901
person.identifier.ciencia-id7414-8AFD-AC4F
person.identifier.ciencia-id6517-B340-F362
person.identifier.orcid0000-0003-4378-0265
person.identifier.orcid0000-0002-3023-1315
person.identifier.orcid0000-0002-5058-2112
person.identifier.ridB-2735-2019
person.identifier.scopus-author-id7004664870
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication2ff7fbcc-2d3e-4eca-8c2a-928b4c3aec73
relation.isAuthorOfPublication559428fd-8556-4a3c-9039-f39c68210715
relation.isAuthorOfPublicationad32fa9b-85eb-4679-a4c9-9f6109423b88
relation.isAuthorOfPublicationad6de30c-87ca-4613-bb87-488dd5d285d0
relation.isAuthorOfPublication.latestForDiscoveryad6de30c-87ca-4613-bb87-488dd5d285d0

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
Milk_enriched_phytosterols.pdf
Tamanho:
161.9 KB
Formato:
Adobe Portable Document Format
Ver/Abrir

Coleções

FM-IMPSP-Artigos em Revistas Internacionais
FM-IB-Artigos em Revistas Internacionais
IMM - Artigos em Revistas Internacionais