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African swine fever virus : cellular and molecular aspects

2021-03-10Capítulo de livro Acesso aberto
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dc.contributor.authorUrbano, A.
dc.contributor.authorForth, J.H.
dc.contributor.authorOlesen, A.S.
dc.contributor.authorZakaryan, H.
dc.contributor.authorFerreira, Fernando
dc.contributor.authorDixon, L.
dc.contributor.authorRasmussen, T.B.
dc.contributor.authorCackett, G.
dc.contributor.authorWerner, F.
dc.contributor.authorKarger, A.
dc.date.accessioned2021-04-11T22:57:07Z
dc.date.available2021-04-11T22:57:07Z
dc.date.issued2021-03-10
dc.description.abstractABSTRACT - Over the last years, African swine fever virus (ASFV) has spread to several European and Asian countries, presently showing an unprecedented geographic distribution. The present chapter focuses on current knowledge and advances in the cellular/molecular features of ASFV, highlighting the gaps and future perspectives. The first half of the chapter addresses the general features of ASFV, its phylogeny and evolution, together with an overview of the viral transcription mechanisms and transcriptomics and the proteomics of ASFV-infected cells. The second half of the chapter summarises the structure and composition of the infectious ASFV particle, the mechanisms that lead to the infection and replication of the virus at the cellular level, and the viral-pig interactions. The last part of the chapter presents an overview of the currently described antiviral agents against ASFV.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationUrbano, A. et al. 2021. African swine fever virus : cellular and molecular aspects. In: Laura Iacolina et al. Understanding and combatting African swine fever. Wageningen: Wageningen Academic Publishers. p. 25-61pt_PT
dc.identifier.doiDOI.10.3920/978-90-8686-910-7_2pt_PT
dc.identifier.isbneISBN: 978-90-8686-910-7
dc.identifier.urihttp://hdl.handle.net/10400.5/21216
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWageningen Academic Publisherspt_PT
dc.relationCOST (European Cooperation in Science and Technology)pt_PT
dc.relation.publisherversionhttps://doi.org/10.3920/978-90-8686-910-7pt_PT
dc.subjectAfrican swine fever viruspt_PT
dc.subjecttranscriptomicspt_PT
dc.subjectproteomept_PT
dc.subjectvirus-host interactionspt_PT
dc.subjectantiviralspt_PT
dc.titleAfrican swine fever virus : cellular and molecular aspectspt_PT
dc.typebook part
dspace.entity.typePublication
oaire.citation.conferencePlaceWageningenpt_PT
oaire.citation.endPage61pt_PT
oaire.citation.startPage25pt_PT
oaire.citation.titleUnderstanding and combatting African Swine Feverpt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typebookPartpt_PT

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