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Parasite sensing of host nutrients and environmental cues

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dc.contributor.authorZuzarte-Luis, Vanessa
dc.contributor.authorMota, Maria M.
dc.date.accessioned2021-09-21T15:56:00Z
dc.date.available2021-09-21T15:56:00Z
dc.date.issued2018
dc.description© 2018 Elsevier Inc.pt_PT
dc.description.abstractParasites undergo complex life cycles that comprise a wide variety of cellular differentiation events in different host compartments and transmission across multiple hosts. As parasites depend on host resources, it is not surprising they have developed efficient mechanisms to sense alterations and adapt to the available resources in a wide range of environments. Here we provide an overview of the nutritional needs of different parasites throughout their diverse life stages and highlight recent insights into strategies that both hosts and parasites have developed to meet these nutritional requirements needed for defense, survival, and replication. These studies will provide the foundation for a systems-level understanding of host-parasite interactions, which will require the integration of molecular, epidemiologic, and mechanistic data and the application of interdisciplinary approaches to model parasite regulatory networks that are triggered by alterations in host resources.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCell Host Microbe. 2018 Jun 13;23(6):749-758pt_PT
dc.identifier.doi10.1016/j.chom.2018.05.018pt_PT
dc.identifier.eissn1934-6069
dc.identifier.issn1931-3128
dc.identifier.urihttp://hdl.handle.net/10451/49568
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/cell-host-and-microbept_PT
dc.subjectLeishmaniapt_PT
dc.subjectPlasmodiumpt_PT
dc.subjectToxoplasmapt_PT
dc.subjectTrypanosomapt_PT
dc.subjectAdaptationpt_PT
dc.subjectHost-parasite interactionspt_PT
dc.subjectMetabolismpt_PT
dc.subjectNutrientspt_PT
dc.subjectSensingpt_PT
dc.titleParasite sensing of host nutrients and environmental cuespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage758pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage749pt_PT
oaire.citation.titleCell Host & Microbept_PT
oaire.citation.volume23pt_PT
person.familyNameZuzarte-Luis
person.familyNameMota
person.givenNameVanessa
person.givenNameMaria Manuel
person.identifier.ciencia-idE511-2580-B7B2
person.identifier.ciencia-id4217-0969-297E
person.identifier.orcid0000-0003-0023-5953
person.identifier.orcid0000-0002-2858-1041
person.identifier.ridM-9105-2013
person.identifier.scopus-author-id6507946873
person.identifier.scopus-author-id7102709816
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication6b0fe267-4183-4475-8bc8-df00b5341030
relation.isAuthorOfPublication0c93cb69-f8fb-4247-8e71-bb9b84de368c
relation.isAuthorOfPublication.latestForDiscovery6b0fe267-4183-4475-8bc8-df00b5341030

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