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The role of the humoral immune response in the molecular evolution of the envelope C2, V3 and C3 regions in chronically HIV-2 infected patients

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Background: This study was designed to investigate, for the first time, the short-term molecular evolution of the HIV-2 C2, V3 and C3 envelope regions and its association with the immune response. Clonal sequences of the env C2V3C3 region were obtained fr. - Fundacao para a Ciencia e Tecnologia [POCTI/ESP/48045]. - This work was supported by Fundacao para a Ciencia e Tecnologia (project POCTI/ESP/48045). Pedro Borrego is supported by a PhD grant from Fundacao para a Ciencia e Tecnologia.

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Virology

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RETROVIROLOGY. - Vol. 5 (SEP 8 2008)

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BIOMED CENTRAL LTD

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