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Advisor(s)
Abstract(s)
Osteoarthritis (OA) is the most commonly diagnosed joint disease in companion animals,
and proper tools are necessary to assess patients and response to treatment. We aimed to perform
the psychometric evaluation of several clinical metrology instruments (CMI), developed to evaluate
pain and assess outcome. Fifty police working dogs with bilateral hip OA were assessed in a
prospective, randomised, double-blinded study. Patients were evaluated using a stance analyser
in six different moments divided over a 180-day period. Pedometer step count, weight-bearing
symmetry index and deviation from normal weight-bearing were calculated and used for criterion
validity. In each evaluation moment, a copy of the Hudson Visual Analogue Scale (HVAS), Canine
Brief Pain Inventory (CBPI), Liverpool Osteoarthritis in Dogs (LOAD) and Canine Orthopaedic Index
(COI) were completed by the dogs’ handlers. Correlations between CMIs were evaluated as construct
validity. Further evaluation was performed with the Kaiser–Meyer–Olin measure of sampling
adequacy, Eigenvalue and scree-plot analysis. Internal consistency was tested with Cronbach’s
α. Significant weak correlation was found between all CMIs and stance analysis symmetry index
measure and deviation, indicating criterion validity. Significant weak correlation was also found
between pedometer count and LOAD plus COI. Cronbach’s α was 0.80 for HVAS, 0.98 for CBPI, 0.97
for LOAD and 0.98 for COI. Significant strong correlation was observed between CMIs, indicating
construct validity. We present criterion and construct validity of these CMIs, which are able to capture
various dimensions of OA. They can be used for the evaluation of osteoarthritis and response to
treatment in dogs.
Description
Research Areas: Agriculture; Veterinary Sciences; Zoology
Keywords
Animal model Dog Osteoarthritis Hip Stance analysis Clinical metrology instruments
Pedagogical Context
Citation
Alves JC, Santos A, Jorge P, Lavrador C, Carreira LM. 2022. Evaluation of Four Clinical Metrology Instruments for the Assessment of Osteoarthritis in Dogs. Animals, 12(20):2808. DOI: https:// doi.org/10.3390/ani12202808
Publisher
MDPI