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Ethnomedicinal, Chemical, and Biological Aspects of Lannea Species—A Review

dc.contributor.authorMalú, Quintino
dc.contributor.authorCaldeira, Gonçalo I.
dc.contributor.authorCatarino, Luís
dc.contributor.authorIndjai, Bucar
dc.contributor.authorda Silva, Isabel Moreira
dc.contributor.authorLima, Beatriz
dc.contributor.authorSilva, Olga
dc.date.accessioned2024-12-20T11:40:47Z
dc.date.available2024-12-20T11:40:47Z
dc.date.issued2024-02
dc.description.abstractLannea L. genus belongs to the Anacardiaceae botanical family and has long been used in traditional medicinal systems of many countries to manage several health conditions, but no studies have been conducted regarding its usefulness as a source of herbal medicine for human use. A literature review was conducted on scientific papers indexed on B-On, Pubmed, and Web of Science databases. Our results showed that medicinal plants from this botanical genus, mostly constituted by bark and leaf, are often used to approach a wide variety of disease symptoms, like fever, inflammatory states, pain, and gastrointestinal disorders. Phytochemical profiles of Lannea species revealed that phenolic acid derivatives including hydroquinones, phenolic acids, flavonoids, condensed tannins, and triterpenoids are the main classes of secondary metabolites present. Among the total of 165 identified compounds, 57 (34.5%) are flavonoids, mostly quercetin- and myricetin-derived flavonols and catechin and epicatechin flavan-3-ol derivatives also containing a galloyl group. In vitro and in vivo studies allowed the identification of 12 different biological activities, amongst which antimicrobial, antioxidant, anti-inflammatory, and cytotoxic activities were the most frequently cited and observed in in vitro essays. Our review contributes useful information for the scientifical validation of the use of Lannea species in traditional medicinal systems and shows that more research needs to be conducted to better understand the concrete utility of these as herbal medicines.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMalú, Q.; Caldeira, G.I.; Catarino, L.; Indjai, B.; da Silva, I.M.; Lima, B.; Silva, O. Ethnomedicinal, Chemical, and Biological Aspects of Lannea Species—A Review. Plants 2024, 13, 690.pt_PT
dc.identifier.doi10.3390/plants13050690pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.5/96549
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationFCT UIDP/04138/2020; https://doi.org/10.54499/UIDP/04138/2020pt_PT
dc.relationFCT UIDB/00329/2020; https://doi.org/10.54499/UIDB/00329/2020pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleEthnomedicinal, Chemical, and Biological Aspects of Lannea Species—A Reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue5pt_PT
oaire.citation.startPage690pt_PT
oaire.citation.titlePlantspt_PT
oaire.citation.volume13pt_PT
person.familyNameCatarino
person.givenNameLuis
person.identifier.ciencia-id2615-C6BE-1540
person.identifier.orcid0000-0002-1261-9076
person.identifier.ridL-8701-2013
person.identifier.scopus-author-id6602434329
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication63b33bc9-857b-412e-a5e5-3977960779f3
relation.isAuthorOfPublication.latestForDiscovery63b33bc9-857b-412e-a5e5-3977960779f3

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