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How different is the dietary pattern in non-alcoholic steatohepatitis patients?

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dc.contributor.authorCortez-Pinto, Helena
dc.contributor.authorJesus, L.
dc.contributor.authorBarros, H.
dc.contributor.authorLopes, C.
dc.contributor.authorMoura, M. C.
dc.contributor.authorCamilo, M. E.
dc.date.accessioned2021-05-11T11:25:29Z
dc.date.available2021-05-11T11:25:29Z
dc.date.issued2006
dc.description© 2006 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. Published by Elsevier Inc. All rights reserved.pt_PT
dc.description.abstractBackground/aims: This study aimed at evaluating whether patients with non-alcoholic steatohepatitis (NASH) had a specific dietary pattern and how it compared with data representative from the same geographical region individuals. Subjects and methods: Clinical, biochemical and anthropometrics: weight, height, body mass index (BMI) and waist circumference were collected in 45 NASH patients. Diet history was assessed using a validated semi-quantitative food frequency questionnaire, analysed with the Food Processor Plus, and was compared, after adjustment for BMI, with data from a sample of 856 free-living individuals, frequency matched for sex and age. Results: Patients' mean age was 49.6+/-10.6 years, 26 F: 19 M, BMI: 31.2+/-5.0 kg/m2. Comparison of their diet history with control data (C) revealed that carbohydrate consumption was lower in patients (P): P-243.6+/-5.7 g vs. C-261.5+/-1.6 g, P<0.05, and most patients had very low fibre intake. Conversely, total fat consumption was higher in patients: P-79.7+/-1.7 g vs. 73.0+/-0.4, P<0.01. A significantly higher intake of n-6 fatty acids (P=0.003) and n-6/n-3 ratio was found in patients, P<0.001. Conclusions: Our results suggest that the quality and combination of carbohydrates and fat intake may be more relevant than their isolated amount; an increased fat intake with an excessive amount of n-6 fatty acids can be implicated in promoting necro-inflammation, and provides further grounds for individualized dietary therapy.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationClin Nutr. 2006 Oct;25(5):816-823pt_PT
dc.identifier.doi10.1016/j.clnu.2006.01.027pt_PT
dc.identifier.eissn1532-1983
dc.identifier.issn0261-5614
dc.identifier.urihttp://hdl.handle.net/10451/47745
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.clinicalnutritionjournal.com/pt_PT
dc.subjectDiet historypt_PT
dc.subjectNutrientspt_PT
dc.subjectNon-alcoholic steatohepatitispt_PT
dc.subjectFibrept_PT
dc.subjectFatpt_PT
dc.subjectn-6 and n-3 fatty acidspt_PT
dc.titleHow different is the dietary pattern in non-alcoholic steatohepatitis patients?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage823pt_PT
oaire.citation.issue5pt_PT
oaire.citation.startPage816pt_PT
oaire.citation.titleClinical Nutritionpt_PT
oaire.citation.volume25pt_PT
person.familyNameCortez-Pinto
person.givenNameHelena
person.identifier.ciencia-idA01C-0511-C986
person.identifier.orcid0000-0002-8537-8744
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication91fdb4b3-d491-4e67-94ff-dcf5013fa1a7
relation.isAuthorOfPublication.latestForDiscovery91fdb4b3-d491-4e67-94ff-dcf5013fa1a7

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