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Diabetes e dislipidémias
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Resumo(s)
Este trabalho, foi realizado no decurso do estágio de natureza profissional que faz parte do plano de estudos do Mestrado em Análises Clínicas da Faculdade de Farmácia da Universidade de Lisboa (FFUL), que decorreu em 2015. É um relatório e serve como elemento de avaliação final. Tem como objetivo descrever as atividades de maior relevo desenvolvidas ao longo do referido estágio.
O estágio laboratorial decorreu em duas Instituições diferentes. No Instituto Português de Oncologia de Lisboa, Francisco Gentil, onde foram realizadas as valências de: Pré-Analítica; Bioquímica Clínica; Imunologia e Virologia; e no Laboratório de Análises Clínicas Dr. Joaquim Chaves, onde foi realizada a valência de Hematologia.
O trabalho está dividido por valências, onde são abordadas as principais atividades desenvolvidas no decurso das mesmas. Dada a extensão das matérias, é feita uma descrição sumária dos principais equipamentos, métodos e ensaios, realizados por valência laboratorial.
A realização deste estágio foi uma mais valia. Com este estágio tive oportunidade de relembrar e refletir sobre conhecimentos adquiridos, durante a frequência das unidades curriculares do curso e aplicá-las em contexto real. Permitiu adquirir novos conhecimentos, tomar contacto com o meio laboratorial e estabelecer relações com profissionais e utentes enriquecedoras e gratificantes, valiosas para o meu desenvolvimento pessoal e profissional no âmbito das análises clínicas.
This study was conducted during the professional internship, done in 2015, that is part integrated of the study plan of the Master in Clinical Analysis of the Faculty of Pharmacy, University of Lisbon (FFUL). This document is a Report and it will also be an element in the final evaluation. The aim of this Report is to describe the most important activities developed during the internship. The internship occurred in a laboratorial context in two different institutions. At the Portuguese Institute of Oncology of Lisbon, Francisco Gentil, where the following valences were performed: Pre-analytical, Clinical Biochemistry, Immunology and Virology, and in the Clinical Analysis Laboratory Dr. Joaquim Chaves, were the valence of Haematology was held. This report is divided by the valences and in each one the main activities developed during the internship are described. Given the extend of the matters, it is made a short description of the main equipment, methods and trials done through the laboratorial valence. The opportunity to develop this professional internship was an asset to me. With this internship I had the opportunity to remind, reflect and apply in real laboratorial context some of the knowledges acquired during the curricular units of the course. The internship also allowed me to acquire new knowledge, to have contact with the laboratorial context and to establish very enrichment and rewarding relations with professional and users, which were very important for my personal and professional development in the clinical analysis.
A diabetes é uma doença metabólica crónica, caracterizada por uma deficiente regulação da glicose pela insulina. Atualmente tem uma elevada prevalência em todo mundo. Constitui um fator de risco para as doenças cardiovasculares, agravado pela sua associação à dislipidemia. Esta monografia é desenvolvida em duas partes. Na primeira é feita uma breve revisão da literatura, sobre os aspetos fisiopatológicos da diabetes e suas complicações. Na segunda, é apresentado um pequeno estudo retrospetivo. Do estudo fizeram parte 74 utentes, portadores de diabetes mellitus 2, seguidos em consulta de Endocrinologia, numa Instituição Hospitalar Psiquiátrica, no ano de 2015. O objetivo do estudo foi caracterizar a população envolvida e avaliar o seu perfil glicémico e lipídico. Os parâmetros analíticos estudados foram: a glicemia em jejum, a hemoglobina glicada, o colesterol total, o LDL-colesterol, o HDL-colesterol e os triglicéridos.
Diabetes is a chronic metabolic disease, characterized by a deficit in the glucose regulation by insulin. Currently it has a high prevalence in all world. Diabetes constitutes a risk factor in cardiovascular diseases aggravated by its association to dyslipidemia. This monography is developed in two parts. In the first part it is made a brief literature review about the main pathophysiological aspects of the diabetes and its complications. In the second part, it is made a short retrospective study. In this study a sample of 74 users, holders of diabetes mellitus 2 was considered. These users were being followed in Endocrinology consultation in a Psychiatric Institution, during the 2015 year. The aim of this study is to characterize the population in the sample and to assess its glycemic and lipid profile. The analytical parameters studied were: fasting blood glucose; glycated haemoglobin; total cholesterol; LDL- cholesterol; HDL- cholesterol and triglycerides.
This study was conducted during the professional internship, done in 2015, that is part integrated of the study plan of the Master in Clinical Analysis of the Faculty of Pharmacy, University of Lisbon (FFUL). This document is a Report and it will also be an element in the final evaluation. The aim of this Report is to describe the most important activities developed during the internship. The internship occurred in a laboratorial context in two different institutions. At the Portuguese Institute of Oncology of Lisbon, Francisco Gentil, where the following valences were performed: Pre-analytical, Clinical Biochemistry, Immunology and Virology, and in the Clinical Analysis Laboratory Dr. Joaquim Chaves, were the valence of Haematology was held. This report is divided by the valences and in each one the main activities developed during the internship are described. Given the extend of the matters, it is made a short description of the main equipment, methods and trials done through the laboratorial valence. The opportunity to develop this professional internship was an asset to me. With this internship I had the opportunity to remind, reflect and apply in real laboratorial context some of the knowledges acquired during the curricular units of the course. The internship also allowed me to acquire new knowledge, to have contact with the laboratorial context and to establish very enrichment and rewarding relations with professional and users, which were very important for my personal and professional development in the clinical analysis.
A diabetes é uma doença metabólica crónica, caracterizada por uma deficiente regulação da glicose pela insulina. Atualmente tem uma elevada prevalência em todo mundo. Constitui um fator de risco para as doenças cardiovasculares, agravado pela sua associação à dislipidemia. Esta monografia é desenvolvida em duas partes. Na primeira é feita uma breve revisão da literatura, sobre os aspetos fisiopatológicos da diabetes e suas complicações. Na segunda, é apresentado um pequeno estudo retrospetivo. Do estudo fizeram parte 74 utentes, portadores de diabetes mellitus 2, seguidos em consulta de Endocrinologia, numa Instituição Hospitalar Psiquiátrica, no ano de 2015. O objetivo do estudo foi caracterizar a população envolvida e avaliar o seu perfil glicémico e lipídico. Os parâmetros analíticos estudados foram: a glicemia em jejum, a hemoglobina glicada, o colesterol total, o LDL-colesterol, o HDL-colesterol e os triglicéridos.
Diabetes is a chronic metabolic disease, characterized by a deficit in the glucose regulation by insulin. Currently it has a high prevalence in all world. Diabetes constitutes a risk factor in cardiovascular diseases aggravated by its association to dyslipidemia. This monography is developed in two parts. In the first part it is made a brief literature review about the main pathophysiological aspects of the diabetes and its complications. In the second part, it is made a short retrospective study. In this study a sample of 74 users, holders of diabetes mellitus 2 was considered. These users were being followed in Endocrinology consultation in a Psychiatric Institution, during the 2015 year. The aim of this study is to characterize the population in the sample and to assess its glycemic and lipid profile. The analytical parameters studied were: fasting blood glucose; glycated haemoglobin; total cholesterol; LDL- cholesterol; HDL- cholesterol and triglycerides.
Descrição
Tese de mestrado, Análises Clínicas, Universidade de Lisboa, Faculdade de Farmácia, 2016
Palavras-chave
Bioquímica Imunologia Virologia Hematologia Diabetes mellitus Dislipidemia Doença cardiovascular Teses de mestrado - 2016