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Patients with undetermined stroke have increased atrial fibrosis : a cardiac magnetic resonance imaging study

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dc.contributor.authorFonseca, Ana Catarina
dc.contributor.authorAlves, Pedro
dc.contributor.authorInácio, Nuno
dc.contributor.authorMarto, João Pedro
dc.contributor.authorViana-Baptista, Miguel
dc.contributor.authorMelo, Teresa Pinho e
dc.contributor.authorFerro, José
dc.contributor.authorAlmeida, Ana G.
dc.date.accessioned2019-03-26T16:09:57Z
dc.date.available2019-03-26T16:09:57Z
dc.date.issued2018
dc.description© 2018 American Heart Association, Inc.pt_PT
dc.description.abstractBackground and Purpose—Some patients with ischemic strokes that are currently classified as having an undetermined cause may have structural or functional changes of the left atrium (LA) and left atrial appendage, which increase their risk of thromboembolism. We compared the LA and left atrial appendage of patients with different ischemic stroke causes using cardiac magnetic resonance imaging. Methods—We prospectively included a consecutive sample of ischemic stroke patients. Patients with structural changes on echocardiography currently considered as causal for stroke in the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) classification were excluded. A 3-T cardiac magnetic resonance imaging was performed. Results—One hundred and eleven patients were evaluated. Patients with an undetermined cause had a higher percentage of LA fibrosis (P=0.03) than patients with other stroke causes and lower, although not statistically significant, values of LA ejection fraction. Patients with atrial fibrillation and undetermined stroke cause showed a similar value of atrial fibrosis. Conclusions—The LA phenotype that was found in patients with undetermined cause supports the hypothesis that an atrial disease may be associated with stroke.pt_PT
dc.description.sponsorshipThis study is funded by “Fundo de Investigação para a Saúde”(FIS-2015-01CCV)pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationStroke. 2018;49:734-737pt_PT
dc.identifier.doi10.1161/STROKEAHA.117.019641pt_PT
dc.identifier.issn0039-2499
dc.identifier.urihttp://hdl.handle.net/10451/37695
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherLippincott, Williams & Wilkinspt_PT
dc.relationFIS-2015-01CCVpt_PT
dc.relation.publisherversionhttps://www.ahajournals.org/journal/strpt_PT
dc.subjectAtrial fibrillationpt_PT
dc.subjectEchocardiographypt_PT
dc.subjectMagnetic resonance imagingpt_PT
dc.subjectStrokept_PT
dc.subjectThromboembolismpt_PT
dc.titlePatients with undetermined stroke have increased atrial fibrosis : a cardiac magnetic resonance imaging studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage737pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage734pt_PT
oaire.citation.titleStrokept_PT
oaire.citation.volume49pt_PT
person.familyNameFonseca
person.familyNamePinho e Melo
person.familyNameMorão Cabral Ferro
person.givenNameAna Catarina
person.givenNameTeresa
person.givenNameJosé Manuel
person.identifier.ciencia-id6F16-7E25-7AAF
person.identifier.orcid0000-0001-6913-5526
person.identifier.orcid0000-0002-0375-0101
person.identifier.orcid0000-0002-2343-9097
person.identifier.scopus-author-id16452610900
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication9b6049cb-46fb-4d04-9d21-94878cc3c818
relation.isAuthorOfPublicatione74412bf-766d-4f86-b55f-76f6a1cb3eb4
relation.isAuthorOfPublication9a568ce6-d218-44fc-982c-0ffe7bffc197
relation.isAuthorOfPublication.latestForDiscovery9b6049cb-46fb-4d04-9d21-94878cc3c818

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