Logo do repositório
 
Publicação

Ultrasound halo sign as a potential monitoring tool for patients with giant cell arteritis: a prospective analysis

2021Artigo científico Acesso restrito
Ver registo simples
dc.contributor.authorPonte, Cristina
dc.contributor.authorMonti, Sara
dc.contributor.authorScirè, Carlo Alberto
dc.contributor.authorDelvino, Paolo
dc.contributor.authorKhmelinskii, Nikita
dc.contributor.authorMilanesi, Alessandra
dc.contributor.authorTeixeira, Vítor
dc.contributor.authorBrandolino, Fabio
dc.contributor.authorSaraiva, Fernando
dc.contributor.authorMontecucco, Carlomaurizio
dc.contributor.authorFonseca, João Eurico
dc.contributor.authorSchmidt, Wolfgang A
dc.contributor.authorLuqmani, Raashid Ahmed
dc.date.accessioned2021-09-23T10:39:16Z
dc.date.available2021-09-23T10:39:16Z
dc.date.issued2021
dc.description© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.pt_PT
dc.description.abstractObjectives: To assess the sensitivity to change of ultrasound halo features and their association with disease activity and glucocorticoid (GC) treatment in patients with newly diagnosed giant cell arteritis (GCA). Methods: Prospective study of patients with ultrasound-confirmed GCA who underwent serial ultrasound assessments of the temporal artery (TA) and axillary artery (AX) at fixed time points. The number of segments with halo and maximum halo intima-media thickness (IMT) was recorded. Time points in which >80% of patients were assessed were considered for analysis. Halo features at disease presentation and first relapse were compared. Results: 49 patients were assessed at 354 visits. Halo sensitivity to change was assessed at weeks 1, 3, 6, 12 and 24 and showed a significant standardised mean difference between all time points and baseline for the TA halo features but only after week 6 for the AX halo features. The number of TA segments with halo and sum and maximum TA halo IMT showed a significant correlation with erythrocyte sedimentation rate (0.41, 0.44 and 0.48), C reactive protein (0.34, 0.39 and 0.41), Birmingham Vasculitis Activity Score (0.29, 0.36 and 0.35) and GC cumulative dose (-0.34, -0.37 and -0.32); no significant correlation was found for the AX halo features. Halo sign was present in 94% of first disease relapses but with a lower mean number of segments with halo and sum of halo IMT compared with disease onset (2.93±1.59 mm vs 4.85±1.51 mm, p=0.0012; 2.01±1.13 mm vs 4.49±1.95 mm, p=0.0012). Conclusions: Ultrasound is a useful imaging tool to assess disease activity and response to treatment in patients with GCA.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationAnn Rheum Dis. 2021 Jul 2:annrheumdis-2021-220306pt_PT
dc.identifier.doi10.1136/annrheumdis-2021-220306pt_PT
dc.identifier.eissn1468-2060
dc.identifier.issn0003-4967
dc.identifier.urihttp://hdl.handle.net/10451/49589
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMJ Publishing Grouppt_PT
dc.relation.publisherversionhttps://ard.bmj.com/pt_PT
dc.subjectGiant cell arteritispt_PT
dc.subjectSystemic vasculitispt_PT
dc.subjectUltrasonographypt_PT
dc.titleUltrasound halo sign as a potential monitoring tool for patients with giant cell arteritis: a prospective analysispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleAnnals of the Rheumatic Diseasespt_PT
person.familyNamePonte
person.familyNameKhmelinskii
person.familyNameTeixeira
person.familyNameSaraiva
person.familyNameFonseca
person.givenNameCristina
person.givenNameNikita
person.givenNameVítor
person.givenNameFernando
person.givenNameJoão
person.identifier.ciencia-id3713-901B-4493
person.identifier.ciencia-idA816-90BB-845E
person.identifier.ciencia-idF310-B85D-57C7
person.identifier.orcid0000-0002-3989-1192
person.identifier.orcid0000-0001-6358-7388
person.identifier.orcid0000-0002-9452-0028
person.identifier.orcid0000-0002-0868-2371
person.identifier.orcid0000-0003-1432-3671
person.identifier.scopus-author-id7101983519
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication22483f4f-a4d7-48f5-9fae-cc5ae926528a
relation.isAuthorOfPublication20951934-70b7-4bda-ba08-498f9742e462
relation.isAuthorOfPublication2b1a93df-b841-475f-b8fd-c162f99d028f
relation.isAuthorOfPublication0a72de9c-e80f-45bf-a536-81cc839b9e72
relation.isAuthorOfPublication1772dc12-7c55-4c76-ae2d-c23270172480
relation.isAuthorOfPublication.latestForDiscovery22483f4f-a4d7-48f5-9fae-cc5ae926528a

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
Ultrasound_halo.pdf
Tamanho:
18.5 MB
Formato:
Adobe Portable Document Format
Ver/Abrir

Coleções

IMM - Artigos em Revistas Internacionais
FM - Artigos em Revistas Internacionais