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Playing evolution in the laboratory: From the first major evolutionary transition to global warming

2018-06-08Artigo científico Acesso aberto
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dc.contributor.authorDe mendonça fragata almeida, Inês
dc.contributor.authorSimões, Pedro
dc.contributor.authorMatos, Margarida
dc.contributor.authorSzathmáry, Eörs
dc.contributor.authorSantos, Mauro
dc.date.accessioned2020-07-15T14:50:08Z
dc.date.available2020-07-15T14:50:08Z
dc.date.issued2018-06-08
dc.description.abstractExperimental evolution allows testing hypothesis derived from theory or from observed patterns in nature. We have designed a droplet-based microfluidic ‘evolution machine’ to test how transient compartmentalization (‘trait-groups’) of independent molecular replicators (likely a critical step in the origin of life) could have prevented the spread of parasitic mutants; that is, inactive RNAs that have been reported to spoil a system of free replicators. In remarkable agreement with the theory, we show that this simple population structure was sufficient to prevent takeover by inactive RNAs. A more complex scenario arises when we use experimental evolution to test field-derived hypothesis; for instance, the idea that temperature is driving genetic spatiotemporal patterns of climate change. In the fly Drosophila subobscura, latitudinal clines in gene arrangement frequencies occur worldwide, and more equatorial gene arrangements are becoming more frequent at higher latitudes as a correlated response to climate change. However, the evolution at different constant temperatures in the laboratory was not consistent with patterns in nature, suggesting some limitations of experimental evolution. Finally, also in D. subobscura, we show that repeatability in experimental evolution is staggeringly consistent for life history traits, making evolution quite predictable and suggesting that laboratory selection can quickly erase differences between populations. Yet, the genetic paths used to attain the same adaptive phenotypes are complex and unpredictable.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFRAGATA, I., SIMÔES, P., MATOS, M., SZATHMÁRY, E. & SANTOS, M. 2018. Playing evolution in the laboratory: From the first major evolutionary transition to global warming. EPL 122 38001. DOI: 10.1209/0295-5075/122/38001pt_PT
dc.identifier.doi10.1209/0295-5075/122/38001pt_PT
dc.identifier.urihttp://hdl.handle.net/10451/44013
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherIOP Publishingpt_PT
dc.relationCentre for Ecology, Evolution and Environmental Changes
dc.relationPREPARE - Predicting the Persistence of Resistance Across Environments
dc.relationGENE EXPRESSION PATTERNS DURING ADAPTATION: AN EXPERIMENTAL EVOLUTION APPROACH
dc.relation.publisherversionhttps://iopscience.iop.org/article/10.1209/0295-5075/122/38001/metapt_PT
dc.subjectExperimental Evolutionpt_PT
dc.subjectEvolutionary noveltiespt_PT
dc.subjectOrigin of lifept_PT
dc.subjectPredictability of Evolutionpt_PT
dc.subjectClimate changept_PT
dc.titlePlaying evolution in the laboratory: From the first major evolutionary transition to global warmingpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleCentre for Ecology, Evolution and Environmental Changes
oaire.awardTitlePREPARE - Predicting the Persistence of Resistance Across Environments
oaire.awardTitleGENE EXPRESSION PATTERNS DURING ADAPTATION: AN EXPERIMENTAL EVOLUTION APPROACH
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FBIA%2F00329%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/JPIAMR%2F0001%2F2016/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/OE/SFRH%2FBPD%2F86186%2F2012/PT
oaire.citation.issue3pt_PT
oaire.citation.startPage38001pt_PT
oaire.citation.titleEPL (Europhysics Letters)pt_PT
oaire.citation.volume122pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream3599-PPCDT
oaire.fundingStreamOE
person.familyNameLopes de Mendonça Fragata Almeida
person.familyNameSimões
person.familyNameMatos
person.givenNameInês Regina
person.givenNamePedro Miguel
person.givenNameMargarida
person.identifierResearcherID: I-9876-2014
person.identifierK-2365-2012
person.identifier.ciencia-idF812-23C0-FEC5
person.identifier.ciencia-id7E14-DE9F-7537
person.identifier.ciencia-id461A-92A5-2FD0
person.identifier.orcid0000-0001-6865-1510
person.identifier.orcid0000-0002-4253-1200
person.identifier.orcid0000-0001-6998-5133
person.identifier.scopus-author-id24474345000
person.identifier.scopus-author-id35586903000
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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