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Análise da revisão Cochrane : administração suplementar de vitamina D para prevenção de cancro em adultos : Cochrane database syst rev. 2014, 6:cd007469

2014Journal article Open access
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dc.contributor.authorCardoso, André Torres
dc.contributor.authorNanji, Liliana Sousa
dc.contributor.authorCosta, João
dc.contributor.authorCarneiro, António Vaz
dc.date.accessioned2020-11-05T12:36:24Z
dc.date.available2020-11-05T12:36:24Z
dc.date.issued2014
dc.descriptionCopyright © Ordem dos Médicos 2014pt_PT
dc.description.abstractVitamin D has been mentioned in the literature has a potentially important agent for preventing the development of tumors, namely breast, colon, prostate and ovary tumors. However, the currently available evidence on the subject is contradictory and inconclusive. In this Cochrane systematic review, patients taking supplemental vitamin D on its various forms (cholecalciferol, ergocalciferol, alfacalcidol or calcitriol), regardless the dose, duration and route of administration, were compared with placebo, healthy adults without any intervention or adults with a disease in a stable phase, non-related with vitamin D metabolism. The results showed that currently, there is no firm evidence that vitamin D supplementation increases or decreases the risk of cancer occurrence, mainly in elderly community-dwelling women. Though at risk of type I errors due to small samples and substantial dropout of participants during the trials, the administration of supplemental cholecalciferol led to a 12% (CI 95%: 2 a 22%) decreased in cancer mortality, while the administration of supplemental vitamin D decreased all-cause mortality by 7% (CI 95%: 2 a 12%). The combined administration of supplements of cholecalciferol and calcium induced an increased incidence of nephrolithiasis.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationActa Med Port 2014 Jul-Aug;27(4):411-413pt_PT
dc.identifier.eissn1646-0758
dc.identifier.issn0870-399X
dc.identifier.urihttp://hdl.handle.net/10451/44791
dc.language.isoporpt_PT
dc.peerreviewedyespt_PT
dc.publisherOrdem dos Médicospt_PT
dc.relation.publisherversionhttps://www.actamedicaportuguesa.com/revista/index.php/amp/indexpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAdultpt_PT
dc.subjectRandomized controlled trials as topicpt_PT
dc.subjectNeoplasms/prevention and controlpt_PT
dc.subjectSystematic reviewspt_PT
dc.subjectVitamin Dpt_PT
dc.titleAnálise da revisão Cochrane : administração suplementar de vitamina D para prevenção de cancro em adultos : Cochrane database syst rev. 2014, 6:cd007469pt_PT
dc.title.alternativeAnalysis of the Cochrane review : vitamin D supplementation for prevention of cancer in adults : Cochrane database syst rev. 2014, 6:cd007469pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage413pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage411pt_PT
oaire.citation.titleActa Médica Portuguesapt_PT
oaire.citation.volume27pt_PT
person.familyNameSousa Nanji
person.familyNameCosta
person.familyNameVaz Carneiro
person.givenNameLiliana
person.givenNameJoão
person.givenNameAntónio
person.identifier480560
person.identifier.orcid0000-0002-1166-5097
person.identifier.orcid0000-0002-5831-4921
person.identifier.orcid0000-0002-2783-0544
person.identifier.ridL-8026-2013
person.identifier.scopus-author-id55499748300
person.identifier.scopus-author-id7006837792
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicatione72a49c2-78a5-4f86-9e55-ed08e491d792
relation.isAuthorOfPublication0924f405-2d3a-4914-9097-24aa639bd97f
relation.isAuthorOfPublication376d157f-1127-4663-9d99-038dac28f37d
relation.isAuthorOfPublication.latestForDiscoverye72a49c2-78a5-4f86-9e55-ed08e491d792

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