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Labdane and kaurane diterpenoids from Plectranthus fruticosus

2003Artigo científico Apenas metadados
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dc.contributor.authorGaspar-Marques, C
dc.contributor.authorSimoes, MF
dc.contributor.authorDuarte, A
dc.contributor.authorRodriguez, B
dc.date.accessioned2015-12-30T10:17:33Z
dc.date.available2015-12-30T10:17:33Z
dc.date.issued2003
dc.description.abstractSix new diterpenoids, three labdane and three kaurane derivatives, have been isolated from an acetone extract of Plectranthus fruticosus together with other already known substances. The structures of these compounds (1-5 and 7) were established mainly by spectroscopic means, particularly by 1D and 2D NMR studies, as well as by some chemical correlations with known diterpenoids. The physical and spectroscopic data of the derivative 11, obtained by hydrolysis of the labdane 2, were identical to those reported for a compound previously isolated from Croton joufra, to which structure 12 had been established erroneously by other authors. Several of the isolated compounds were tested as antimicrobial agents against three bacteria strains and one yeast strain, but only 4 showed a moderate inhibitory activity against Staphylococcus aureus.
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dc.identifier.citationJOURNAL OF NATURAL PRODUCTS. - Vol. 66, n. 4 (APR 2003), p. 491-496
dc.identifier.doihttp://dx.doi.org/10.1021/np020493g
dc.identifier.issn0163-3864
dc.identifier.urihttp://hdl.handle.net/10451/21130
dc.language.isoeng
dc.publisherAMER CHEMICAL SOC
dc.subjectPlant Sciences
dc.subjectChemistry, Medicinal
dc.subjectPharmacology & Pharmacy
dc.titleLabdane and kaurane diterpenoids from Plectranthus fruticosus
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage496por
oaire.citation.startPage491por
oaire.citation.titleJOURNAL OF NATURAL PRODUCTSpor
oaire.citation.volumeVol. 66por
rcaap.rightsrestrictedAccess
rcaap.typearticle

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