Role of multidrug resistance-associated protein 1 expression in the in vitro susceptibility of rat nerve cell to unconjugated bilirubin

Falcao, A. S.; Bellarosa, C.; Fernandes, A.; Brito, M. A.; Silva, R. F. M.; Tiribelli, C.; Brites, D.

http://hdl.handle.net/10451/21563

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Nerve cell injury by unconjugated bilirubin (ILICB) has been implicated in brain damage during neonatal hyperbilirubinemia, particularly in the preterm newborn. Recently, it was shown that UCB is a substrate for the multidrug resistance-associated protein