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Vasculitis and breast cancer: mind the hint

dc.contributor.authorEsperança Martins, Miguel
dc.contributor.authorEvangelista, Vasco
dc.contributor.authorFernandes, Salomão
dc.contributor.authorAlmeida, Raquel
dc.date.accessioned2021-11-30T15:09:44Z
dc.date.available2021-11-30T15:09:44Z
dc.date.issued2021
dc.description© 2021 The Author(s). Published by S. Karger AG, Basel. This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission.pt_PT
dc.description.abstractDiffuse alveolar haemorrhage related to an anti-neutrophil cytoplasmic antibody (ANCA)-associated small vessel vasculitis is an extremely rare form of presentation of breast cancer. Here we report the case of a 77-year-old woman with a histological diagnosis of a papillary ductal carcinoma of the breast presenting with a diffuse alveolar haemorrhage secondary to a perinuclear ANCA-associated vasculitis. To our knowledge, this is the first case ever reported of a diffuse alveolar haemorrhage related to an ANCA-associated small vessel vasculitis as a form of presentation of breast cancer. The therapeutic approach of this paraneoplastic vasculitis included the use of corticosteroids and plasmapheresis, a very useful technique to remove endothelial aggressors (circulating antibodies) as a strategy to earn time for a proper therapeutic decision specifically directed for disease modification, but that can also be associated with several severe adverse effects, which are illustrated in our case.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCase Rep Oncol. 2021 Mar 22;14(1):550-560pt_PT
dc.identifier.doi10.1159/000514729pt_PT
dc.identifier.eissn1662-6575
dc.identifier.urihttp://hdl.handle.net/10451/50226
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKargerpt_PT
dc.relation.publisherversionhttps://www.karger.com/Journal/Home/239061pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectDiffuse alveolar haemorrhagept_PT
dc.subjectParaneoplastic vasculitispt_PT
dc.subjectPlasmapheresispt_PT
dc.subjectBreast cancerpt_PT
dc.titleVasculitis and breast cancer: mind the hintpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage560pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage550pt_PT
oaire.citation.titleCase Reports in Oncologypt_PT
oaire.citation.volume14pt_PT
person.familyNameEsperança Martins
person.givenNameMiguel
person.identifier1201606
person.identifier.orcid0000-0002-6858-7341
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicatione73cbe66-c79a-4f6b-9bed-b3af464000db
relation.isAuthorOfPublication.latestForDiscoverye73cbe66-c79a-4f6b-9bed-b3af464000db

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