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Assembly of the nucleolus: in need of revision
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Resumo(s)
Our current view of the nucleolus has been shaped by the concept that the organization of this prominent compartment within the nucleus is primarily dictated by its function, the making of ribosome subunits. Whether ribosome biogenesis is framed by a dedicated nucleolar scaffold has remained unclear. In this issue of The EMBO Journal, Caudron‐Herger and colleagues present evidence for a nucleolar skeleton composed of non‐coding RNA enriched in Alu repeat elements.
Descrição
© 2015 The Author
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Contexto Educativo
Citação
EMBO J. 2015 Nov 12;34(22):2731-2732
Editora
EMBO Press