Publication
Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial
| dc.contributor.author | Videira-Silva, Antonio | |
| dc.contributor.author | Santos, Inês | |
| dc.contributor.author | Freaza, Dalise | |
| dc.contributor.author | Gameiro, Mariana | |
| dc.contributor.author | Sardinha, Luís B. | |
| dc.contributor.author | Fonseca, Helena | |
| dc.date.accessioned | 2024-07-23T14:13:14Z | |
| dc.date.available | 2024-07-23T14:13:14Z | |
| dc.date.issued | 2024 | |
| dc.description | © The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. | pt_PT |
| dc.description.abstract | Purpose: The present study aimed to explore the influence of diet and physical activity (PA) changes on bone mineral content (BMC) and density (BMD) alterations in adolescents with obesity undergoing a weight loss program. Methods: Six-month longitudinal data from 71 adolescents (aged 15.1 [± 1.6] years; 57.7% girls) with a BMI z-score of 3.03 (± 0.78), previously recruited for the PAC-MAnO trial, were analyzed using Generalized Estimation Equations for over time changes and linear regressions with BMC, BMD and BMD z-score as dependent variables, adjusting for confounders (including type of exercise- aerobic vs. combined). Results: Adjusting for confounders, changes in carbohydrate (CH) and protein content showed to positively and negatively predict BMD z-score variance, respectively (β = 0.44, 95%CI: 0.01, 0.04, p < .001); β = -0.57, 95%CI: -0.06, -0.03, p < .001), yet no associations were found between PA and bone-related parameters. Combined exercise showed better results on BMC compared to aerobic exercise (β = 0.09, 95%CI: 0.05 to 0.13, p < .001). Conclusions: Increased CH content, instead of protein, may be associated with BMD improvements in adolescents with obesity. Type of exercise may moderate the impact of PA on bone health. Trial registration: Clinicaltrials.gov NCT02941770. What is Known • Adolescents with obesity may be at a higher risk of osteopenia/osteoporosis • Obesity and inadequate diet and physical activity (PA) may have an adverse effect on bone metabolism What is New • Improvements in adiposity and muscle mass and increased diet carbohydrate content are associated with bone mineral density (BMD) improvements • Type of exercise (i.e., combined training vs. aerobic) may moderate the impact of PA on BMD, and calcium intake may mediate this impact. | pt_PT |
| dc.description.sponsorship | AVS was supported by the Portuguese Foundation for Science and Technology (SFRH/BD/130193/2017). Open access funding provided by FCT|FCCN (b-on). AVS was supported by the Portuguese Foundation for Science and Technology (SFRH/BD/130193/2017). | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Eur J Pediatr. 2024 Jun 27 | pt_PT |
| dc.identifier.doi | 10.1007/s00431-024-05659-4 | pt_PT |
| dc.identifier.eissn | 1432-1076 | |
| dc.identifier.issn | 0340-6199 | |
| dc.identifier.uri | http://hdl.handle.net/10451/65417 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Springer Nature | pt_PT |
| dc.relation | SFRH/BD/130193/2017 | pt_PT |
| dc.relation.publisherversion | https://link.springer.com/journal/431 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Adolescents | pt_PT |
| dc.subject | Bone health | pt_PT |
| dc.subject | Diet | pt_PT |
| dc.subject | Exercise | pt_PT |
| dc.subject | Obesity | pt_PT |
| dc.subject | Physical activity | pt_PT |
| dc.title | Dietary content and combined training, but not daily physical activity, are associated with 6-month bone mineral changes in adolescents with obesity: a secondary analysis of the PAC-MAnO trial | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.title | European Journal of Pediatrics | pt_PT |
| person.familyName | Videira Silva | |
| person.familyName | Chaparro Roque dos Santos | |
| person.familyName | Sardinha | |
| person.familyName | Fonseca | |
| person.givenName | Antonio | |
| person.givenName | Inês | |
| person.givenName | Luis | |
| person.givenName | Helena | |
| person.identifier | N-1856-2016 | |
| person.identifier.ciencia-id | DD12-3E66-20BB | |
| person.identifier.ciencia-id | 8E14-4B1D-9F4E | |
| person.identifier.ciencia-id | A812-2D8E-1BC9 | |
| person.identifier.ciencia-id | 3F17-A0D4-D0C6 | |
| person.identifier.orcid | 0000-0002-8209-1676 | |
| person.identifier.orcid | 0000-0002-1638-8551 | |
| person.identifier.orcid | 0000-0002-6230-6027 | |
| person.identifier.orcid | 0000-0003-0565-1403 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 3aa7bf17-683a-4293-b91c-6f31d56ab463 | |
| relation.isAuthorOfPublication | 6e672e07-deab-42de-ac5a-8d91cd617873 | |
| relation.isAuthorOfPublication | 6bddc71b-cb91-40b4-a59e-2964f0d14f32 | |
| relation.isAuthorOfPublication | f4765445-af43-4a33-b056-4489e86ccc42 | |
| relation.isAuthorOfPublication.latestForDiscovery | f4765445-af43-4a33-b056-4489e86ccc42 |