Advisor(s)
Abstract(s)
A new protocol has been developed for the generation of alkylidenecarbene derivatives of monosaccharides based on the reaction of trimethylsilylazide and Bu2SnO with alpha-cyanomesylates derived from uloses. When this method is applied to conveniently functionalized carbohydrate derivatives it provides novel heterocyclic ring systems by the rare 1,6-C-H or 1,5-O-Si insertion reactions.
Description
Keywords
Biochemistry & Molecular Biology Chemistry, Organic
Pedagogical Context
Citation
JOURNAL OF CARBOHYDRATE CHEMISTRY. - Vol. 24, n. 40333 (MAY-AUG 2005), p. 369-377
Publisher
TAYLOR & FRANCIS INC