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Anthelmintic efficacy in sheep and goats under different management and deworming systems in the region of Lisbon and Tagus Valley, Portugal
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Advisor(s)
Abstract(s)
ABSTRACT - Infections caused by gastrointestinal parasites have been described worldwide as one of
the most important issues impacting small ruminant production. The systematic administration
of anthelmintic (AH) drugs without following good practice principles has led to an increase in
anthelmintic resistance (AR). There is scarce information regarding AH efficacy in small ruminants
in Portugal. This study aimed to characterize by in vivo methods the presence and level of AR in
four farms in the region of Lisbon and Tagus Valley. All four farms kept small herds in extensive
management systems and used different deworming protocols. The active substances used were
fenbendazole and a combination of mebendazole plus closantel in a dosage according to the manufacturers’ instructions. On day 0 (T0), fecal samples were collected from all study animals, and animals
in the treatment group (n = 40) were dewormed with the AH previously chosen by the assistant
veterinarian. Animals in the control group (n = 30) did not receive any AH drug. The fecal sample
collection was repeated on day 15 (T15), and the control group was treated. Egg counts were performed using the McMaster method for the eggs per gram (EPG), and AR was evaluated by the fecal
egg count reduction test (FECRT) with a 95% confidence level (CL). The results from this experiment
indicated that the four farms presented AR with two farms to fenbendazole (FECRT of 48% and 85%)
and two farms to mebendazole plus closantel (FECRT of 66% and 79%). These results indicate that the
gastrointestinal parasites of the four studied Portuguese farms are resistant to benzimidazoles, which
suggests an increase in AR regarding nematodes in small ruminant production systems in Portugal
Description
Research Areas: Microbiology
Keywords
Gastrointestinal parasites Small ruminants Anthelmintic efficacy FECRT Lisbon and Tagus Valley Portugal
Pedagogical Context
Citation
Antunes MI, Lima MS, Stilwell G, Romeiras MI, Fragoso L, Madeira de Carvalho LM. 2022. Anthelmintic efficacy in sheep and goats under different management and deworming systems in the region of Lisbon and Tagus Valley, Portugal. Pathogens, 11(12):1457. DOI: https://doi.org/10.3390/pathogens11121457
Publisher
MDPI