Logo do repositório
 
Publicação

Evolution of diffusion tensor imaging parameters after acute subarachnoid haemorrhage : a prospective cohort study

2016Artigo científico Acesso restrito
Ver registo simples
dc.contributor.authorFragata, Isabel
dc.contributor.authorCanhão, Patrícia
dc.contributor.authorAlves, Marta
dc.contributor.authorPapoila, Ana Luísa
dc.contributor.authorCanto-Moreira, Nuno
dc.date.accessioned2021-01-05T16:13:40Z
dc.date.available2021-01-05T16:13:40Z
dc.date.issued2016
dc.description© Springer-Verlag Berlin Heidelberg 2016.pt_PT
dc.description.abstractIntroduction: Few studies assessed diffusion tensor imaging (DTI) changes in the acute phase of subarachnoid haemorrhage (SAH). We prospectively evaluated DTI parameters in the acute phase of SAH and 8-10 days after and analysed whether changes could be related to SAH severity or to the development of delayed cerebral ischemia (DCI). Methods: Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) changes over time were assessed in a prospective cohort of patients with acute SAH. Two MRI studies were performed at <72 h (MRI-1) and 8-10 days (MRI-2). DTI parameters were recorded in 15 ROIs. Linear mixed regression models were used. Results: Forty-two patients were included. Subtle changes in DTI parameters were found between MRI-1 and MRI-2. At the posterior limb of internal capsule (PLIC), a weak evidence of a 0.02 mean increase in FA (p = 0.064) and a 17.55 × 10-6 mm2/s decrease in ADC (p = 0.052) were found in MRI-2. Both FA and ADC changed over time at the cerebellum (increase of 0.03; p = 0.017; decrease of 34.73 × 10-6 mm2/s; p = 0.002, respectively). Patients with DCI had lower FA values on MRI-1 and lower ADC on MRI-2, although not reaching statistical significance, compared to non-DCI patients. DTI parameters on MRI-1 were not correlated to clinical admission scales. Conclusion: ADC and FA values show subtle changes over time in acute SAH at the PLIC and cerebellum although not statistically associated with the severity of SAH or the occurrence of DCI. However, DTI changes occurred mainly in DCI patients, suggesting a possible role of DTI as a marker of DCI.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationNeuroradiology. 2017 Jan;59(1):13-21pt_PT
dc.identifier.doi10.1007/s00234-016-1774-ypt_PT
dc.identifier.eissn1432-1920
dc.identifier.issn0028-3940
dc.identifier.urihttp://hdl.handle.net/10451/45675
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Naturept_PT
dc.relation.publisherversionhttps://www.springer.com/journal/234pt_PT
dc.subjectDelayed cerebral ischemiapt_PT
dc.subjectDiffusion tensor imagingpt_PT
dc.subjectSubarachnoid haemorrhagept_PT
dc.titleEvolution of diffusion tensor imaging parameters after acute subarachnoid haemorrhage : a prospective cohort studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage21pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage13pt_PT
oaire.citation.titleNeuroradiologypt_PT
oaire.citation.volume59pt_PT
person.familyNameCanhão
person.givenNamePatrícia
person.identifier.ciencia-id8F12-6A40-BE2E
person.identifier.orcid0000-0003-3816-0416
person.identifier.scopus-author-id6603685711
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicatione9d5a53f-d0d3-4cc4-9807-879ef76be505
relation.isAuthorOfPublication.latestForDiscoverye9d5a53f-d0d3-4cc4-9807-879ef76be505

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
Evolution_tensor.pdf
Tamanho:
931.17 KB
Formato:
Adobe Portable Document Format
Ver/Abrir

Coleções

FM - Artigos em Revistas Internacionais