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Advisor(s)
Abstract(s)
O objetivo deste estudo é a avaliação da exposição ao Metilmercúrio (MeHg) em potenciais populações de Risco em Portugal.
Para a realização deste estudo foi selecionada uma população de grávidas dos SESARAM (Serviços de Saúde da Região Autónoma da Madeira). Esta população foi escolhida porque, sendo a Madeira uma Ilha e sendo a atividade piscatória uma fonte de subsistência, o peixe é um dos alimentos mais consumidos.
De acordo com estudos prévios, o consumo de peixe contaminado com MeHg na gravidez pode levar a atrasos no neurodesenvolvimento dos fetos.
De forma a averiguar a frequência e as espécies de peixe mais consumidos bem como as características sociodemográficas da população foram realizados inquéritos.
O número médio de refeições por semana encontrado foi 2,51 e o Índice de Risco médio detetado foi de 1,02, sendo que valores superiores a 1 indicam risco para a saúde.
Foram recolhidas em simultâneo com a realização dos inquéritos, amostras de sangue das grávidas nas quais foram determinados os teores de mercúrio. Esta medição funciona como biomarcador de exposição a este metal.
The aim of this study is to assess the potential exposure to methylmercury (MeHg) in populations at risk in Portugal. For this study it was selected a population of pregnant women from SESARAM (Serviços de Saúde da Região Autónoma da Madeira). Madeira, being an island, have as source of subsistence fishery activities. Then fish is one of the most consumed food, this is why Madeira is chosen as population to study. According to previous studies, the consumption of fish contaminated with MeHg in pregnancy can lead to neurodevelopmental delay of fetuses. In order to determine the frequency and species of fish most consumed as well as the socio-demographic characteristics of the population a cross-sectional survey was conducted. The average number of meals per week was 2.51 and the Risk Index average detected was 1.02, considering that values greater than 1indicate health risk. Blood samples of pregnant women participating in the study were simultaneously collected and the levels of mercury were determined. This measure serves as a biomarker of exposure to this metal.
The aim of this study is to assess the potential exposure to methylmercury (MeHg) in populations at risk in Portugal. For this study it was selected a population of pregnant women from SESARAM (Serviços de Saúde da Região Autónoma da Madeira). Madeira, being an island, have as source of subsistence fishery activities. Then fish is one of the most consumed food, this is why Madeira is chosen as population to study. According to previous studies, the consumption of fish contaminated with MeHg in pregnancy can lead to neurodevelopmental delay of fetuses. In order to determine the frequency and species of fish most consumed as well as the socio-demographic characteristics of the population a cross-sectional survey was conducted. The average number of meals per week was 2.51 and the Risk Index average detected was 1.02, considering that values greater than 1indicate health risk. Blood samples of pregnant women participating in the study were simultaneously collected and the levels of mercury were determined. This measure serves as a biomarker of exposure to this metal.
Description
Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2013
Keywords
Metilmercúrio Mercúrio Gravidez Índice de Risco (IR) Biomarcador Peixe Madeira Mestrado Integrado - 2013