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Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets
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Advisor(s)
Abstract(s)
Background: The ability of a high level of dietary Arthrospira platensis, individually or in combination with two
exogenous carbohydrate-degrading enzymes (lysozyme and Rovabio®), to improve systemic antioxidant potential
and hepatic lipid metabolism was tested in piglets. Forty male post-weaned piglets, sons of Large White × Landrace
sows crossed with Pietrain boars, were allocated into 4 groups (n = 10) and fed during 28 days one of the following
diets: 1) a control basal diet (cereal and soybean meal); 2) a basal diet with 10% of A. platensis (AP); 3) the AP diet
supplemented with 0.005% of Rovabio® (AP + R); 4) the AP diet supplemented with 0.01% of lysozyme (AP + L).
Results: Arthrospira platensis decreased BW gain of piglets, regardless the addition of feed enzymes. The majority of
plasma metabolites were affected by diets. A. platensis increased total lipids, total cholesterol and LDL-cholesterol,
without changing hepatic fatty acid content or modulating, in an expressive manner, the transcriptional profile of
lipid sensitive mediators. The antioxidant potential in general, and total carotenoids in particular, were improved by
the microalga, regardless lysozyme or Rovabio®.
Conclusions: Summing up, A. platensis, individually and combined with feed enzymes, impacts negatively on
piglets’ growth but improves the systemic antioxidant potential and changes plasma lipids with a minor
modulation on related hepatic metabolic pathways
Description
Research Article
Keywords
Arthrospira platensis enzymes antioxidant potential hepatic lipid metabolism piglets
Pedagogical Context
Citation
Santos Madeira et al. BMC Veterinary Research (2021) 17:158
Publisher
BMC