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Actinic keratosis treated by topical Aloe barbadensis Mill. (Aloe Vera) leaf gel

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Aloe vera is a cactus-resembling, succulent, watery plant, extensively used by the cosmetic and food industries[1]. Actinic keratosis, a dysplastic skin lesion commonly found in low Fitzpatrick skin type individuals[2] associated with chronic UV exposure[3,4], is defined by a scaly, keratotic or pigmented papule on an erythematous base[5]. The precursor to skin field cancerization is actinic keratosis, which is an area of photodamaged skin containing subclinical genetic changes, a direct consequence of intraepithelial UV-induced damage[6,7]. Actinic keratosis, as a precancerous lesion, can develop into an invasive squamous cell carcinoma (ISCC)[6]. There is no way to predict which lesions will progress to ISCC, with guidelines recommending treatment of all actinic keratosis lesions[8- 11]. Field-directed therapies are used to treat multiple actinic keratosis lesions and contiguous field cancerization subclinical lesions[12]

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Aloe vera Actinic keratosis

Contexto Educativo

Citação

Direito, R., Ferreira, J.B., Ferreira, R.B., Lima, A. (2021). Actinic keratosis treated by topical Aloe barbadensis Mill. (Aloe Vera) leaf gel. Academia Letters, Article 721

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