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Advisor(s)
Abstract(s)
Aloe vera is a cactus-resembling, succulent, watery plant, extensively used by the cosmetic
and food industries[1]. Actinic keratosis, a dysplastic skin lesion commonly found in low
Fitzpatrick skin type individuals[2] associated with chronic UV exposure[3,4], is defined by
a scaly, keratotic or pigmented papule on an erythematous base[5].
The precursor to skin field cancerization is actinic keratosis, which is an area of photodamaged
skin containing subclinical genetic changes, a direct consequence of intraepithelial
UV-induced damage[6,7]. Actinic keratosis, as a precancerous lesion, can develop into an
invasive squamous cell carcinoma (ISCC)[6]. There is no way to predict which lesions will
progress to ISCC, with guidelines recommending treatment of all actinic keratosis lesions[8-
11].
Field-directed therapies are used to treat multiple actinic keratosis lesions and contiguous
field cancerization subclinical lesions[12]
Description
Keywords
Aloe vera Actinic keratosis
Pedagogical Context
Citation
Direito, R., Ferreira, J.B., Ferreira, R.B., Lima, A. (2021). Actinic keratosis treated by topical Aloe barbadensis Mill. (Aloe Vera) leaf gel. Academia Letters, Article 721
Publisher
Academia